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Pregnancy Outcome with Intrauterine Insemination in Patients with Unexplained Recurrent Abortion Whose Partners Have Abnormal Hypo-Osmotic Swelling Test | ||
| Iranian Journal of Medical Sciences | ||
| مقاله 2، دوره 34، شماره 3، آذر 2009، صفحه 172-176 اصل مقاله (59.38 K) | ||
| نوع مقاله: Original Article(s) | ||
| نویسندگان | ||
| Jaleh Zolghadri* ؛ Zohreh Tavana؛ Saeed Alborzi؛ Talie Kazerooni | ||
| چکیده | ||
| Background: Recurrent abortion is defined as three or more consecutive pregnancy losses. We aimed to determine the relationship between male sperm parameters and hypo-osmotic swelling score and recurrent abortion. We also studied whether washing of spermatozoa and intrauterine insemination in patients with recurrent miscarriage and low score hypo-osmotic swelling test in male partners could improve the outcome of pregnancy. Methods: Between February 2003 and September 2006 in gynecology clinics affiliated to Shiraz University of Medical Sciences, 176 women with a history of recurrent abortion and their male partners were selected as study group. And 159 healthy and fertile couples without a history of recurrent abortion were selected as control group. The relationship between male sperm parameters and hypo-osmotic swelling test and recurrent spontaneous abortion in their female partners was evaluated after intrauterine insemination for those with abnormal hypo-osmotic swelling test. Outcome of pregnancy in patients with recurrent abortion whose male partners had low score hypo-osmotic swelling test was evaluated after intrauterine insemination. Results: Low scores of hypo-osmotic swelling test were more frequently seen in the study group than the controls: 116 (65%) versus 24 (15%). The mean hypo-osmotic swelling score was significantly lower in the study group (p < 0.001). The outcome of pregnancy improved after intrauterine insemination in those with low score hypo-osmotic swelling test. The pregnancy success rate in the treated group (pregnant with intrauterine insemination) was 77.77% while in the untreated group (pregnant without intrauterine insemination) was 30.76% with a success rate ratio of 2.04. Conclusion: There was a positive relationship between low hypo-osmotic swelling test score in male partners and recurrent abortion in their wives. Intrauterine insemination improved the outcome of pregnancy in these couples. | ||
| کلیدواژهها | ||
| Recurrent abortion؛ intrauterine؛ insemination | ||
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