LinkedIn

 آمار

تعداد نشریات20
تعداد شماره‌ها1,149
تعداد مقالات10,518
تعداد مشاهده مقاله45,415,630
تعداد دریافت فایل اصل مقاله11,291,432
Ansari, Mansour, Dehsara, Farzin, Mohammadianpanah, Mohammad, Mosalaei, Ahmad, Omidvari, Shapour, Ahmadloo, Niloofar. (1393). Treatment Results and Prognostic Indicators in Thymic Epithelial Tumors: A Clinicopathological Analysis of 45 Patients. سامانه مدیریت نشریات علمی, 39(4), 341-349.
Mansour Ansari; Farzin Dehsara; Mohammad Mohammadianpanah; Ahmad Mosalaei; Shapour Omidvari; Niloofar Ahmadloo. "Treatment Results and Prognostic Indicators in Thymic Epithelial Tumors: A Clinicopathological Analysis of 45 Patients". سامانه مدیریت نشریات علمی, 39, 4, 1393, 341-349.
Ansari, Mansour, Dehsara, Farzin, Mohammadianpanah, Mohammad, Mosalaei, Ahmad, Omidvari, Shapour, Ahmadloo, Niloofar. (1393). 'Treatment Results and Prognostic Indicators in Thymic Epithelial Tumors: A Clinicopathological Analysis of 45 Patients', سامانه مدیریت نشریات علمی, 39(4), pp. 341-349.
Ansari, Mansour, Dehsara, Farzin, Mohammadianpanah, Mohammad, Mosalaei, Ahmad, Omidvari, Shapour, Ahmadloo, Niloofar. Treatment Results and Prognostic Indicators in Thymic Epithelial Tumors: A Clinicopathological Analysis of 45 Patients. سامانه مدیریت نشریات علمی, 1393; 39(4): 341-349.

Treatment Results and Prognostic Indicators in Thymic Epithelial Tumors: A Clinicopathological Analysis of 45 Patients

Iranian Journal of Medical Sciences
مقاله 4، دوره 39، شماره 4، مهر 2014، صفحه 341-349    اصل مقاله (536.72 K)
نوع مقاله: Original Article(s)
نویسندگان
Mansour Ansari1؛ Farzin Dehsara2؛ Mohammad Mohammadianpanah* 3؛ Ahmad Mosalaei4؛ Shapour Omidvari3؛ Niloofar Ahmadloo3
1Department of Radiation Oncology, Nemazee Teaching Hospital, Shiraz University of Medical Sciences, Shiraz, Iran
2Student Research Committee, Nemazee Teaching Hospital, Shiraz University of Medical Sciences, Shiraz, Iran
3Colorectal Research Center, Shahid Faghihi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran
4Shiraz Institute for Cancer Research, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
چکیده
Background: Thymomas are rare epithelial tumors arising from thymus gland. This study aims at investigating the clinical presentation, prognostic factors and treatment outcome of forty five patients with thymoma and thymic carcinoma. Methods: Forty-five patients being histologically diagnosed with thymoma or thymic carcinoma that were treated and followed-up at a tertiary academic hospital during January 1987 and December 2008 were selected for the present study. Twelve patients were solely treated with surgery, 14 with surgery followed by adjuvant radiotherapy, 12 with sequential combined treatment of surgery, radiotherapy and/or chemotherapy and 7 with non-surgical approach including radiotherapy and/or chemotherapy. Tumors were classified based on the new World Health Organization (WHO) histological classification. Results: There were 18 women and 27 men with a median age of 43 years. Twelve patients (26.7%) had stage I, 7 (17.8%) had stage II, 23 (51%) had stage III and 2 (4.5%) had stage IV disease. Tumors types were categorized as type A (n=4), type AB (n=10), type B1 (n=9), type B2 (n=10), type B3 (n=5) and type C (n=7). In univariate analysis for overall survival, disease stage (P=0.001), tumor size (P=0.017) and the extent of surgical resection (P<0.001) were prognostic factors. Regarding the multivariate analysis, only the extent of the surgical resection (P<0.001) was the independent prognostic factor and non-surgical treatment had a negative influence on the survival. The 5-year and 10-year overall survival rates were 70.8% and 62.9%, respectively. Conclusion: Complete surgical resection is the most important prognostic factor in patients with thymic epithelial tumors.
کلیدواژه‌ها
Thymic neoplasms؛ Prognosis؛ Surgery؛ Radiotherapy
آمار
تعداد مشاهده مقاله: 3,312
تعداد دریافت فایل اصل مقاله: 1,408


سامانه مدیریت نشریات علمی. قدرت گرفته از سیناوب