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Refractory Angioedema in a Patient with Systemic Lupus Erythematosus | ||
Iranian Journal of Medical Sciences | ||
مقاله 12، دوره 40، شماره 4، مهر 2015، صفحه 372-375 اصل مقاله (610.56 K) | ||
نوع مقاله: Case Report(s) | ||
نویسندگان | ||
Zahra Habibagahi* 1؛ Jamshid Ruzbeh2؛ Vahide Yarmohammadi3؛ Malihe Kamali3؛ Mohammad Hassan Rastegar3 | ||
11Department of Rheumatology, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran; and Department of Internal Medicine, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran | ||
2Department of Nephrology, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran; and Department of Internal Medicine, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran | ||
3Department of Internal Medicine, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran | ||
چکیده | ||
Angioedema secondary to C1 inhibitor deficiency has been rarely reported to be associated with systemic lupus erythematosus. A genetic defect of C1 inhibitor produces hereditary angioedema, which is usually presented with cutaneous painless edema, but edema of the genital area, gastrointestinal and laryngeal tracts have also been reported.In lupus patients, angioedema may be the result of an acquired type of C1 inhibitor deficiency, most probably due to antibody formation directed against the C1 inhibitor molecule. Herein we report a new case of lupus nephritis that developed angioedema and a rapid course of disease progression with acute renal failure and alveolar hemorrhage without response to high dose steroid and plasmapheresis. | ||
کلیدواژهها | ||
Systemic lupus erythematosus؛ Angioedema؛ Enalapril | ||
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