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ebrahimpour, adel, Mirbolook, Ahamadreza, okhovatpour, mohammadali, sajadi, mohammadreza, makvandi, kamyar, mousavi, mohamad sadegh, saghari, sepehr, sadighi, mehrdad. (1397). The Relationship between Plasma Levels of Interleukin-6, Multiple Organ Dysfunction and Mortality in Orthopedic Patients. سامانه مدیریت نشریات علمی, 15(2), 156-164. doi: 10.22034/iji.2018.39379
adel ebrahimpour; Ahamadreza Mirbolook; mohammadali okhovatpour; mohammadreza sajadi; kamyar makvandi; mohamad sadegh mousavi; sepehr saghari; mehrdad sadighi. "The Relationship between Plasma Levels of Interleukin-6, Multiple Organ Dysfunction and Mortality in Orthopedic Patients". سامانه مدیریت نشریات علمی, 15, 2, 1397, 156-164. doi: 10.22034/iji.2018.39379
ebrahimpour, adel, Mirbolook, Ahamadreza, okhovatpour, mohammadali, sajadi, mohammadreza, makvandi, kamyar, mousavi, mohamad sadegh, saghari, sepehr, sadighi, mehrdad. (1397). 'The Relationship between Plasma Levels of Interleukin-6, Multiple Organ Dysfunction and Mortality in Orthopedic Patients', سامانه مدیریت نشریات علمی, 15(2), pp. 156-164. doi: 10.22034/iji.2018.39379
ebrahimpour, adel, Mirbolook, Ahamadreza, okhovatpour, mohammadali, sajadi, mohammadreza, makvandi, kamyar, mousavi, mohamad sadegh, saghari, sepehr, sadighi, mehrdad. The Relationship between Plasma Levels of Interleukin-6, Multiple Organ Dysfunction and Mortality in Orthopedic Patients. سامانه مدیریت نشریات علمی, 1397; 15(2): 156-164. doi: 10.22034/iji.2018.39379

The Relationship between Plasma Levels of Interleukin-6, Multiple Organ Dysfunction and Mortality in Orthopedic Patients

Iranian Journal of Immunology
مقاله 7، دوره 15، شماره 2، شهریور 2018، صفحه 156-164    اصل مقاله (170.42 K)
نوع مقاله: Short Paper
شناسه دیجیتال (DOI): 10.22034/iji.2018.39379
نویسندگان
adel ebrahimpour1؛ Ahamadreza Mirbolook2؛ mohammadali okhovatpour1؛ mohammadreza sajadi1؛ kamyar makvandi1؛ mohamad sadegh mousavi2؛ sepehr saghari2؛ mehrdad sadighi* 1
1Taleghani Hospital, Research Development Committee, School of Medicine, Shahid Beheshti University of Medical Science, Tehran, Iran
2Poursina Hospital, Guilan University of Medical Sciences, Rasht, Iran
چکیده
Background: Interleukin 6 (IL-6) functions as both a pro-inflammatory cytokine and an anti-inflammatory cytokine. Objective: To evaluate the levels of IL-6 in patients with multiple organ dysfunction syndrome (MODS). Methods: Level of IL-6 was assessed and recorded for 14 days subsequent to the injury in 161 multiple trauma patients. MODS were diagnosed using Marshal Score. Injury Severity Scoring (ISS) was measured for all patients. Results: The results of this study indicated that there was a significant relationship between the level of IL-6 and ISS on the post trauma days number one and two (P=0.0001). The high level of IL-6 on the post trauma day number 2 was associated with high mortality rate. Conclusion: Our study suggests the second day as the golden time for measuring the serum levels of IL-6. These findings warn us to take more health care actions in patients with higher serum levels of IL-6 on the second day.
کلیدواژه‌ها
IL6؛ Mortality Rate؛ Multiple Organ Dysfunction؛ Multiple Trauma؛ Prognosis
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