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Pouralibaba, Firouz, Babaloo, Zohreh, Pakdel, Farzaneh, Abdollahian, Tahmoores, Pourzare, Solmaz. (1391). Elevated Levels of Interleukin-23 in Sera of Patients with Pemphigus Vulgaris. سامانه مدیریت نشریات علمی, 9(4), 261-265. doi: 10.22034/iji.2012.16880
Firouz Pouralibaba; Zohreh Babaloo; Farzaneh Pakdel; Tahmoores Abdollahian; Solmaz Pourzare. "Elevated Levels of Interleukin-23 in Sera of Patients with Pemphigus Vulgaris". سامانه مدیریت نشریات علمی, 9, 4, 1391, 261-265. doi: 10.22034/iji.2012.16880
Pouralibaba, Firouz, Babaloo, Zohreh, Pakdel, Farzaneh, Abdollahian, Tahmoores, Pourzare, Solmaz. (1391). 'Elevated Levels of Interleukin-23 in Sera of Patients with Pemphigus Vulgaris', سامانه مدیریت نشریات علمی, 9(4), pp. 261-265. doi: 10.22034/iji.2012.16880
Pouralibaba, Firouz, Babaloo, Zohreh, Pakdel, Farzaneh, Abdollahian, Tahmoores, Pourzare, Solmaz. Elevated Levels of Interleukin-23 in Sera of Patients with Pemphigus Vulgaris. سامانه مدیریت نشریات علمی, 1391; 9(4): 261-265. doi: 10.22034/iji.2012.16880

Elevated Levels of Interleukin-23 in Sera of Patients with Pemphigus Vulgaris

Iranian Journal of Immunology
مقاله 7، دوره 9، شماره 4، اسفند 2012، صفحه 261-265    اصل مقاله (198.4 K)
نوع مقاله: Short Paper
شناسه دیجیتال (DOI): 10.22034/iji.2012.16880
نویسندگان
Firouz Pouralibaba1؛ Zohreh Babaloo2؛ Farzaneh Pakdel* 1؛ Tahmoores Abdollahian1؛ Solmaz Pourzare1
1Department of Oral Medicine, Faculty of Dentistry
2Department of Immunology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
چکیده
Background: Pemphigus vulgaris, a chronic mucocutaneous disease, is the most prevalent type of pemphigus which manifests with development of bullae and erosions on skin and mucosal membranes.
Objectives: To investigate the potential role of IL-23 in pemphigus vulgaris.
Methods: In this study, 30 patients with pemphigus vulgaris and 30 healthy individuals were selected according to inclusion and exclusion criteria. Measurement of IL-23 serum levels in blood samples was conducted by ELISA. Data was analyzed using Student’s t-test for comparison of IL-23 levels between the two groups.
Results: Mean serum levels of IL-23 in patients with pemphigus and healthy controls were 25.1 ± 4.2 and 17.9 ± 4.7 pg/ml, respectively (p<0.05).
Conclusions: Based on the findings of this study, serum levels of IL-23 were higher in patients with pemphigus in comparison to healthy individuals with no clinical significance.
کلیدواژه‌ها
autoimmune disease؛ Interleukin-23؛ Pemphigus Vulgaris
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