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Disseminated Bacillus Calmette-Guérin Disease after BCG Vaccination: A Case Report from China | ||
Iranian Journal of Immunology | ||
مقاله 7، دوره 12، شماره 1، خرداد 2015، صفحه 70-73 اصل مقاله (94.58 K) | ||
نوع مقاله: Case Report | ||
نویسندگان | ||
Luoya Ling1؛ Youqing Wang2؛ Ye Ding2؛ Lin Zheng3؛ Xiaohua Qi1؛ Mingjuan Jin2؛ Kun Chen2؛ Shuyun Xie* 1 | ||
1Institute of Immunization and Prevention, Zhejiang Center for Disease Control and Prevention | ||
2Department of Epidemiology and Biostatistics, Zhejiang University School of Public Health | ||
3Institute of Immunization and Prevention, Xihu District Center for Disease Control and Prevention, Hangzhou, China | ||
چکیده | ||
Background: Bacillus Calmette-Guérin (BCG) vaccination is recommended for newborn infants worldwide to prevent tuberculosis. However, complications do occur inevitably in a very low rate, among which the most serious is disseminated disease. The disseminated bacillus Calmette–Guérin disease is a rare disease with high fatality, and can be seen among persons with an underlying immunodeficiency. Case presentation: We report a 4-month-old male infant presenting with recurrent fever, an isolated left axillary massand swelling at the site of BCG inoculation. The cellular immune function analysis showed that the value of CD4/CD8 was 0.994, indicating the existence of immunodeficiency.The results of blood culture and throat swab culture showed conditional pathogen infection. He died of cardiopulmonary failure. Conclusion: In this case, necropsy played a significant role in the final diagnosis of disseminated pulmonary tuberculosis. | ||
کلیدواژهها | ||
Bacillus Calmette-Guérin (BCG)؛ immunodeficiency؛ Pathogen؛ infection؛ Tuberculosis؛ Vaccination | ||
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