Introduction: Integrating artificial intelligence (AI)—particularly generative AI and large language models (LLMs)—into health professions education offers substantial pedagogical opportunities, while highlighting critical gaps in existing ethical and regulatory frameworks. This critical narrative review examines how contemporary literature conceptualizes and addresses these challenges. Methods: Publications from 2020–2025 were identified through searching PubMed, Scopus, and ERIC, focusing on AI, medical and health professions education, ethics, governance, and regulation. The initial search yielded 452 records; following two-stage screening (title/abstract and full-text review), thirty-four sources met the pre-defined inclusion criteria. These sources, including empirical studies, systematic reviews, policy documents, and conceptual papers, were included. Reflexive thematic analysis was used to synthesize the findings, while SANRA (Scale for the Assessment of Narrative Review Articles) informed the weighting of sources, which were categorized into high-, moderate-, and low-weight tiers. Results: Four themes emerged: 1) a regulatory vacuum marked by policy lag and fragmented institutional responses; 2) reinterpretation of autonomy, beneficence, nonmaleficence, and justice in relation to opaque, datadriven systems, 3) generative AI’s impact on scholarship, authorship, and academic integrity; and 4) equity, bias, and professional identity formation in AImediated learning environments. Integrating these themes with crosssector frameworks and the NIST AI Risk Management Framework, the review develops a riskbased governance taxonomy for AI in Health Professions Education, distinguishing low, medium and highrisk educational use cases. Conclusion: This synthesis indicates that current literature favors evolving beyond reactive policies. Consequently, we propose a theoretical shift toward risk-proportionate governance. We suggest that human-in-the-loop pedagogy should be prioritized as a conceptual framework to guide future research and policy development, rather than presenting it as a validated outcome. |
- Bleakley A. Medical Humanities and Medical Education: How the medical humanities can shape better doctors [Internet]. London: Taylor and Francis; 2016 [Cited 2026 May 24]. 1–264 p. Available from: https://www.taylorfrancis.com/books/mono/10.4324/9781315771724/medical-humanities-medical-education-alan-bleakley.
- Sallam M, Sallam M. Ethical aspects of implementing generative artificial intelligence in medical education: a narrative review. History and Philosophy of Medicine. 2025;7(4):20.
- Busch F, Adams LC, Bressem KK. Biomedical Ethical Aspects towards the Implementation of Artificial Intelligence in Medical Education. Med Sci Educ. 2023;33(4):1007–12.
- Mennella C, Maniscalco U, De Pietro G, Esposito M. Ethical and regulatory challenges of AI technologies in healthcare: A narrative review. Heliyon. 2024;10(4):e26297.
- Masters K. Ethical use of Artificial Intelligence in Health Professions Education: AMEE Guide No. 158. Med Teach. 2023;45(6):574–84.
- Franco D’Souza R, Mathew M, Mishra V, Surapaneni KM. Twelve tips for addressing ethical concerns in the implementation of artificial intelligence in medical education. Med Educ Online. 2024;29(1):2330250.
- Floridi L, Cowls J, Beltrametti M, Chatila R, Chazerand P, Dignum V, et al. AI4People-An Ethical Framework for a Good AI Society: Opportunities, Risks, Principles, and Recommendations. Minds Mach (Dordr). 2018;28(4):689–707.
- Obermeyer Z, Powers B, Vogeli C, Mullainathan S. Dissecting racial bias in an algorithm used to manage the health of populations. Science (1979). 2019;366(6464):447–53.
- Patino GA, Amiel JM, Brown M, Lypson ML, Chan TM. The Promise and Perils of Artificial Intelligence in Health Professions Education Practice and Scholarship. Acad Med. 2024;99(5):477–81.
- Byrne D. A worked example of Braun and Clarke’s approach to reflexive thematic analysis. Quality & Quantity. 2021;56(3):1391–412.
- Tran M, Balasooriya C, Jonnagaddala J, Leung GKK, Mahboobani N, Ramani S, et al. Situating governance and regulatory concerns for generative artificial intelligence and large language models in medical education. npj Digital Medicine. 2025;8(1):315.
- Rush E, Byram JN, Garnett CN, DeVaul N, Smith L, Checchi M, et al. An audit of AI-related documents across U.S. medical schools: A framework-based qualitative content analysis. Med Teach. 2025;48(3):493-505.
- Hamilton A. Artificial Intelligence and Healthcare Simulation: The Shifting Landscape of Medical Education. Cureus. 2024;16(5):e59747.
- Ichikawa T, Olsen E, Vinod A, Glenn N, Hanna K, Lund GC, et al. Generative Artificial Intelligence in Medical Education—Policies and Training at US Osteopathic Medical Schools: Descriptive Cross-Sectional Survey. JMIR Med Educ. 2025;11:e58766.
- Lee J, Wu AS, Li D, Kulasegaram K (mahan). Artificial Intelligence in Undergraduate Medical Education: A Scoping Review. Acad Med. 2021;96(11S):S62–70.
- Tran M, Balasooriya C, Semmler C, Rhee J. Generative artificial intelligence: the ‘more knowledgeable other’ in a social constructivist framework of medical education. npj Digital Medicine 2025 8:1. 2025;8(1):430.
- Foltynek T, Bjelobaba S, Glendinning I, Khan ZR, Santos R, Pavletic P, et al. ENAI Recommendations on the ethical use of Artificial Intelligence in Education. International Journal for Educational Integrity. 2023;19(1):12.
- Group Russell. Russell Group principles on the use of generative AI tools in education [Internet]. 2023 [Cited 2025 Dec 19]. Available from: https://nationalcentreforai.jiscinvolve.org/wp/2023/05/11/generative-ai-primer/.
- The General Medical Council [Internet]. 2025 [Cited 2025 Dec 19]. Artificial intelligence and innovative technologies: GMC. Available from: https://www.gmc-uk.org/professional-standards/learning-materials/artificial-intelligence-and-innovative-technologies?utm_source=chatgpt.com.
- Rees G, Nowell L, Risling T. Shaping the Future of Digital Health Education in Canada: Prioritizing Competencies for Health Care Professionals Using the Quintuple Aim. JMIR Med Educ. 2025;11:e75904.
- TEQSA. Gen AI strategies for research training: Emerging practice. Australian Government: TEQSA; 2025.
- Asiedu MN, Dieng A, Haykel I, Rostamzadeh N, Pfohl S, Nagpal C, et al. The Case for Globalizing Fairness: A Mixed Methods Study on Colonialism, AI, and Health in Africa. Proceedings of the 4th ACM Conference on Equity and Access in Algorithms, Mechanisms, and Optimization. Africa: EAAMO; 2024.
- Yu L, Zhai X. Use of artificial intelligence to address health disparities in low- and middle-income countries: a thematic analysis of ethical issues. Public Health. 2024;234:77–83.
- Weidener L, Fischer M. Proposing a Principle-Based Approach for Teaching AI Ethics in Medical Education. JMIR Med Educ. 2024;10(1):e55368.
- Knopp MI, Warm EJ, Weber D, Kelleher M, Kinnear B, Schumacher DJ, et al. AI-Enabled Medical Education: Threads of Change, Promising Futures, and Risky Realities Across Four Potential Future Worlds. JMIR Med Educ. 2023;9(1):e50373.
- Katznelson G, Gerke S. The need for health AI ethics in medical school education. Adv Health Sci Educ Theory Pract. 2021;26(4):1447–58.
- Stokel-Walker C. ChatGPT listed as author on research papers: many scientists disapprove. Nature. 2023;613(7945):620–1.
- Masters K, Herrmann-Werner A, Festl-Wietek T, Taylor D. Preparing for Artificial General Intelligence (AGI) in Health Professions Education: AMEE Guide No. 172. Med Teach. 2024;46(10):1258–71.
- Almansour M, Mohammad Alfhaid F. Generative artificial intelligence and the personalization of health professional education A narrative review. Medicine (United States). 2024;103(31):e38955.
- Lu Q. Development of generative artificial intelligence in medical education: a bibliometric profiling. Front Educ (Lausanne). 2025;10:1613067.
- Ahmed Y. Utilization of ChatGPT in Medical Education: Applications and Implications for Curriculum Enhancement. Acta Informatica Medica. 2023;31(4):300.
- Masters K, MacNeil H, Benjamin J, Carver T, Nemethy K, Valanci-Aroesty S, et al. Artificial Intelligence in Health Professions Education assessment: AMEE Guide No. 178. Med Teach. 2025; 47(9):1410-24.
- Sukhera J. Narrative Reviews: Flexible, Rigorous, and Practical. J Grad Med Educ. 2022;14(4):414–7.
- Grant MJ, Booth A. A typology of reviews: An analysis of 14 review types and associated methodologies. Health Info Libr J. 2009;26(2):91–108.
- Furley P, Goldschmied N. Systematic vs. Narrative Reviews in Sport and Exercise Psychology: Is Either Approach Superior to the Other? Frontiers in Psychology. Front Psychol. 2021;12:685082.
- Ballantine J, Boyce G, Stoner G. A critical review of AI in accounting education: Threat and opportunity. Critical Perspectives on Accounting. 2024;99:102711.
- Tolsgaard MG, Pusic MV, Sebok-Syer SS, Gin B, Svendsen MB, Syer MD, et al. The fundamentals of Artificial Intelligence in medical education research: AMEE Guide No. 156. Med Teach. 2023;45(6):565–73.
- Jiang T, Er S, Heron MJ, Zhu KJ, Yang R. Artificial Intelligence Use in Academic Applicant Screening: A Systematic Review. Plast Reconstr Surg Glob Open. 2025;13(10):e7177.
- Herschbach L, Festl-Wietek T, Stegemann-Philipps C, Sonanini A, Herrmann B, Erschens R, et al. Evaluation of an AI-Based Chatbot Providing Real-Time Feedback in Communication Training for Mental Health Care Professionals: Proof-of-Concept Observational Study. J Med Internet Res. 2025;27:e82818.
- Temper M, Tjoa S, David L. Higher Education Act for AI (HEAT-AI): a framework to regulate the usage of AI in higher education institutions. Front Educ (Lausanne). 2025;10:1505370.
- Purdy RJ. Toward a Certification Framework for AI Governance in Education: Design Principles for a Sector-Appropriate Standard [Internet]. 2026 Feb [Cited 2026 Apr 29]. Available from: https://papers.ssrn.com/abstract=6193658 doi:10.2139/SSRN.6193658.
- Rai S, Verma K, Yadav V. Generative AI in Medical Pharmacology: Balancing Educational Benefits and Hallucination Risks Running Title: AI Hallucinations in Pharmacology Teaching. International Journal of Science and Research. 2025;14(4):1158–69.
- Simoni J, Urtubia-Fernandez J, Mengual E, Simoni DA, Royo M, Egaña-Yin D, et al. Artificial intelligence in undergraduate medical education: an updated scoping review. BMC Med Educ. 2025;25(1):1609.
- Sasseville M, Yousefi F, Ouellet S, Naye F, Stefan T, Carnovale V, et al. The Impact of AI Scribes on Streamlining Clinical Documentation: A Systematic Review. Healthcare (Switzerland). 2025;13(12):1447.
- Khakpaki A. Advancements in artificial intelligence transforming medical education: a comprehensive overview. Med Educ Online. 2025;30(1):2542807.
- Chan A, Rahimi-Ardabilli H, Rogers WA, Coiera E. The real-world impact of artificial intelligence ethics frameworks across a decade in healthcare: a scoping review. Journal of the American Medical Informatics Association. 2025;32(11):1767–77.
- Bouhouita-Guermech S, Gogognon P, Bélisle-Pipon JC. Specific challenges posed by artificial intelligence in research ethics. Front Artif Intell. 2023;6:1149082.
- Sass R. Defining dangerous AI: existential risk, power-intelligence, and the limits of AGI. AI and Ethics. 2025;5(5):5557–73.
- Jha D, Durak G, Sharma V, Keles E, Cicek V, Zhang Z, et al. A Conceptual Framework for Applying Ethical Principles of AI to Medical Practice. Bioengineering. 2025;12(2):180.
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