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Briones-Zamora, Killen H., Polanco Montero, Ana, Monroy Castro, Jessica, Carrera-Cantos, Ana Victoria, Arteaga Ocaña, Karelys Nicole, Briones-Zamora, Anahí D., Briones-Claudett, Killen H.. (1405). Unifocal Frontal Bone Langerhans Cell Histiocytosis Presenting as Persistent Post-Traumatic Swelling in a Child with an Asthma Exacerbation: A Case Report. سامانه مدیریت نشریات علمی, (), -. doi: 10.30476/ijms.2026.110654.4637
Killen H. Briones-Zamora; Ana Polanco Montero; Jessica Monroy Castro; Ana Victoria Carrera-Cantos; Karelys Nicole Arteaga Ocaña; Anahí D. Briones-Zamora; Killen H. Briones-Claudett. "Unifocal Frontal Bone Langerhans Cell Histiocytosis Presenting as Persistent Post-Traumatic Swelling in a Child with an Asthma Exacerbation: A Case Report". سامانه مدیریت نشریات علمی, , , 1405, -. doi: 10.30476/ijms.2026.110654.4637
Briones-Zamora, Killen H., Polanco Montero, Ana, Monroy Castro, Jessica, Carrera-Cantos, Ana Victoria, Arteaga Ocaña, Karelys Nicole, Briones-Zamora, Anahí D., Briones-Claudett, Killen H.. (1405). 'Unifocal Frontal Bone Langerhans Cell Histiocytosis Presenting as Persistent Post-Traumatic Swelling in a Child with an Asthma Exacerbation: A Case Report', سامانه مدیریت نشریات علمی, (), pp. -. doi: 10.30476/ijms.2026.110654.4637
Briones-Zamora, Killen H., Polanco Montero, Ana, Monroy Castro, Jessica, Carrera-Cantos, Ana Victoria, Arteaga Ocaña, Karelys Nicole, Briones-Zamora, Anahí D., Briones-Claudett, Killen H.. Unifocal Frontal Bone Langerhans Cell Histiocytosis Presenting as Persistent Post-Traumatic Swelling in a Child with an Asthma Exacerbation: A Case Report. سامانه مدیریت نشریات علمی, 1405; (): -. doi: 10.30476/ijms.2026.110654.4637

Unifocal Frontal Bone Langerhans Cell Histiocytosis Presenting as Persistent Post-Traumatic Swelling in a Child with an Asthma Exacerbation: A Case Report

Iranian Journal of Medical Sciences
مقالات آماده انتشار، اصلاح شده برای چاپ، انتشار آنلاین از تاریخ 07 مهر 1405    اصل مقاله (1.36 M)
نوع مقاله: Case Report
شناسه دیجیتال (DOI): 10.30476/ijms.2026.110654.4637
نویسندگان
Killen H. Briones-Zamora* 1؛ Ana Polanco Montero2؛ Jessica Monroy Castro2؛ Ana Victoria Carrera-Cantos2؛ Karelys Nicole Arteaga Ocaña2؛ Anahí D. Briones-Zamora2؛ Killen H. Briones-Claudett1، 2
1Faculty of Medical Sciences, Universidad de Especialidades Espíritu Santo, Samborondón, Ecuador
2Medical Education and Research, Briones PulmoCare, Guayaquil, Ecuador
چکیده
Langerhans cell histiocytosis (LCH) is a rare disorder characterized by the clonal proliferation of Langerhans cells, and osseous involvement is the most frequent manifestation in pediatric patients. Although pulmonary involvement is recognized in LCH, respiratory presentations typically reflect direct pulmonary or airway disease rather than reversible obstructive symptoms. We report the case of a 4-year-old child with persistent, painful frontal swelling following minor trauma, which was initially presumed to be a post-traumatic hematoma. During the diagnostic course, the patient developed an asthma exacerbation that improved with bronchodilator and corticosteroid therapy. Imaging revealed a solitary osteolytic lesion of the frontal bone, and histopathological examination confirmed unifocal LCH. No clinical or chest radiographic evidence of pulmonary involvement was identified. This case underscored that persistent post-traumatic cranial swelling warrants imaging and histopathological evaluation, and highlights that the concurrent asthma exacerbation represents a temporal clinical overlap without proven causality. 

تازه های تحقیق

Killen H. Briones-Zamora (Google Scholar)

کلیدواژه‌ها
Histiocytosis؛ Langerhans-cell؛ Osteolysis؛ Wheezing
مراجع
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