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Abdi Vadig, Zahra, Zamani, Hamed, Kani, Amir- Abbas, Keramat Jou, Samira, Molazadeh, Mikaeil. (1405). The Effect of Oral Contrast Agent on Tomotherapy Plans for Esophageal Carcinoma. سامانه مدیریت نشریات علمی, (), -.
Zahra Abdi Vadig; Hamed Zamani; Amir- Abbas Kani; Samira Keramat Jou; Mikaeil Molazadeh. "The Effect of Oral Contrast Agent on Tomotherapy Plans for Esophageal Carcinoma". سامانه مدیریت نشریات علمی, , , 1405, -.
Abdi Vadig, Zahra, Zamani, Hamed, Kani, Amir- Abbas, Keramat Jou, Samira, Molazadeh, Mikaeil. (1405). 'The Effect of Oral Contrast Agent on Tomotherapy Plans for Esophageal Carcinoma', سامانه مدیریت نشریات علمی, (), pp. -.
Abdi Vadig, Zahra, Zamani, Hamed, Kani, Amir- Abbas, Keramat Jou, Samira, Molazadeh, Mikaeil. The Effect of Oral Contrast Agent on Tomotherapy Plans for Esophageal Carcinoma. سامانه مدیریت نشریات علمی, 1405; (): -.

The Effect of Oral Contrast Agent on Tomotherapy Plans for Esophageal Carcinoma

Journal of Biomedical Physics and Engineering
مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 02 شهریور 1405
نوع مقاله: Original Research
نویسندگان
Zahra Abdi Vadig1؛ Hamed Zamani1؛ Amir- Abbas Kani2؛ Samira Keramat Jou3؛ Mikaeil Molazadeh* 1
1Department of Medical Physics, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
2Department of Radiotherapy, Imam Khomeini Hospital, Ardabil University of Medical Sciences, Ardabil, Iran
3Department of Radiotherapy, Shahid Madani Hospital, Tabriz University of Medical Sciences, Tabriz, Iran
چکیده
Background: The use of Contrast Agents (CAs) in radiotherapy enhances target volume contouring accuracy, but may influence dosimetric outcomes for the Planning Target Volume (PTV) and Organs-at-Risk (OARs).
Objective: This study aimed to investigate the dosimetric effects of Oral Contrast Agent (OCA) in Helical Tomotherapy (HT) treatment plans for patients with Esophageal Cancer (EC).
Material and Methods: In this experimental study, a total of 15 patients (8 females, 7 males; mean age 59.35±8.42 years) underwent two Computed Tomography (CT) scans: non-Contrast-Enhanced CT (non-CECT) and CECT. The original HT plans were performed on CECT images using the Precision Treatment Planning System (TPS), and then original plans were transferred into non-CECT images using the patient QA plan module. Dosimetric parameters, including Homogeneity Index (HI), Conformity Index (CI), Dx, Vx, and gamma index were compared between two plans.
Results: Dosimetric evaluation showed an increase in PTV dose metrics in CECT images, with significant differences in D98, D95, and Dmin. Also, a significant difference was observed in HI (0.03±0.01 to 0.05±0.02) and CI (0.85±0.06 to 0.80±0.08) indices. Notably, the use of OCA led to reduced mean radiation doses to the OARs (heart, lungs, and spinal cord) demonstrating a statistically significant decrease in mean lung dose (-0.14±0.25 Gy).  
Conclusion: Our findings demonstrate that the use of OCAs in Helical Tomotherapy Plans significantly enhances dosimetric outcomes by improving target volume coverage and reducing radiation exposure to critical organs.
کلیدواژه‌ها
Esophageal Neoplasms؛ Contrast Media؛ Radiation Dosage؛ Radiotherapy Planning؛ Helical Tomotherapy
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تعداد مشاهده مقاله: 21
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