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Priastana, I Ketut Andika, Solehah, Eka Lutfiatus. (1405). Physiological Effects of Sargassum Modified Cassava Composite Diet in Malnourished Mice. سامانه مدیریت نشریات علمی, 11(3), 552-559. doi: 10.30476/ijns.2026.109263.1593
I Ketut Andika Priastana; Eka Lutfiatus Solehah. "Physiological Effects of Sargassum Modified Cassava Composite Diet in Malnourished Mice". سامانه مدیریت نشریات علمی, 11, 3, 1405, 552-559. doi: 10.30476/ijns.2026.109263.1593
Priastana, I Ketut Andika, Solehah, Eka Lutfiatus. (1405). 'Physiological Effects of Sargassum Modified Cassava Composite Diet in Malnourished Mice', سامانه مدیریت نشریات علمی, 11(3), pp. 552-559. doi: 10.30476/ijns.2026.109263.1593
Priastana, I Ketut Andika, Solehah, Eka Lutfiatus. Physiological Effects of Sargassum Modified Cassava Composite Diet in Malnourished Mice. سامانه مدیریت نشریات علمی, 1405; 11(3): 552-559. doi: 10.30476/ijns.2026.109263.1593

Physiological Effects of Sargassum Modified Cassava Composite Diet in Malnourished Mice

International Journal of Nutrition Sciences
مقاله 18، دوره 11، شماره 3، آذر 2026، صفحه 552-559    اصل مقاله (385.76 K)
نوع مقاله: Original Article
شناسه دیجیتال (DOI): 10.30476/ijns.2026.109263.1593
نویسندگان
I Ketut Andika Priastana* ؛ Eka Lutfiatus Solehah
Universitas Triatma Mulya, Badung, Indonesia
چکیده
Background: Malnutrition remains a significant public health concern, impairing both physical growth and physiological functions. Functional foods derived from local resources such as Sargassum sp. and modified cassava flour (MOCAF) may offer a potential strategy to improve nutritional status. This study aimed to examine the effect of a combination of Sargassum sp. from Jembrana coastal waters and MOCAF from Manihot esculenta Crantz on malnutrition in mice based on physical assessment.
Methods: A pre-experimental one group pre- and post-test design was conducted using 39 male Mus musculus (6-8 weeks old, 15–25 g). Mice were induced for malnutrition and then received orally a combination of Sargassum sp. and MOCAF for 14 days at ratios of 90:10 (P1), 85:15 (P2), and 80:20 (P3) at 3-5 g/day. Physical parameters were measured before and after interventions.
Results: Administration of Sargassum sp.–MOCAF combination could significantly improve body weight and APGAR (activity, pulse, grimace, appearance and respiration assessments) score in all groups. Body weight increased significantly in P1 (p=0.001), P2 (p=0.001), and P3 (p=0.001), with P2 showing the largest effect. APGAR score improved significantly in P1, P2, and P3 (all p<0.001) too, with P2 showing the highest improvement.
Conclusion: The Sargassum sp. and MOCAF combination effectively enhanced the physical condition of malnourished mice, with the 85:15 ratio (P2) to be the optimal. This combination showed promise as a functional food intervention against malnutrition, warranting further molecular and clinical studies.

تازه های تحقیق

I Ketut Andika Priastana (Google Scholar)

کلیدواژه‌ها
Sargassum؛ Cassava؛ Malnutrition؛ APGAR score؛ Mouse
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