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Priastana, IKetut Andika, Solehah, Eka Lutfiatus. (1405). Physiological Effects of Sargassum Modified Cassava Composite Diet in Malnourished Mice. سامانه مدیریت نشریات علمی, (), -. doi: 10.30476/ijns.2026.109263.1593
IKetut Andika Priastana; Eka Lutfiatus Solehah. "Physiological Effects of Sargassum Modified Cassava Composite Diet in Malnourished Mice". سامانه مدیریت نشریات علمی, , , 1405, -. doi: 10.30476/ijns.2026.109263.1593
Priastana, IKetut Andika, Solehah, Eka Lutfiatus. (1405). 'Physiological Effects of Sargassum Modified Cassava Composite Diet in Malnourished Mice', سامانه مدیریت نشریات علمی, (), pp. -. doi: 10.30476/ijns.2026.109263.1593
Priastana, IKetut Andika, Solehah, Eka Lutfiatus. Physiological Effects of Sargassum Modified Cassava Composite Diet in Malnourished Mice. سامانه مدیریت نشریات علمی, 1405; (): -. doi: 10.30476/ijns.2026.109263.1593

Physiological Effects of Sargassum Modified Cassava Composite Diet in Malnourished Mice

International Journal of Nutrition Sciences
مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 01 شهریور 1405    اصل مقاله (382.51 K)
نوع مقاله: Original Article
شناسه دیجیتال (DOI): 10.30476/ijns.2026.109263.1593
نویسندگان
IKetut Andika Priastana* ؛ Eka Lutfiatus Solehah
Universitas Triatma Mulya, Badung, Indonesia
چکیده
Background: Malnutrition remains a significant public health concern, impairing both physical growth and physiological functions. Functional foods derived from local resources such as Sargassum sp. and modified cassava flour (MOCAF) may offer a potential strategy to improve nutritional status. This study aimed to examine the effect of a combination of Sargassum sp. from Jembrana coastal waters and MOCAF from Manihot esculenta Crantz on malnutrition in mice based on physical assessment.
Methods: A pre-experimental one group pre- and post-test design was conducted using 39 male Mus musculus (6-8 weeks old, 15–25 g). Mice were induced for malnutrition and then received orally a combination of Sargassum sp. and MOCAF for 14 days at ratios of 90:10 (P1), 85:15 (P2), and 80:20 (P3) at 3-5 g/day. Physical parameters were measured before and after interventions.
Results: Administration of Sargassum sp.–MOCAF combination could significantly improve body weight and APGAR (activity, pulse, grimace, appearance and respiration assessments) score in all groups. Body weight increased significantly in P1 (p=0.001), P2 (p=0.001), and P3 (p=0.001), with P2 showing the largest effect. APGAR score improved significantly in P1, P2, and P3 (all p<0.001) too, with P2 showing the highest improvement.
Conclusion: The Sargassum sp. and MOCAF combination effectively enhanced the physical condition of malnourished mice, with the 85:15 ratio (P2) to be the optimal. This combination showed promise as a functional food intervention against malnutrition, warranting further molecular and clinical studies.

تازه های تحقیق

IKetut Andika Priastana (Google Scholar)

کلیدواژه‌ها
Sargassum؛ Cassava؛ Malnutrition؛ APGAR score؛ Mous
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