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Montazeri, Faridokht, Alijanpour, Morteza, Ebrahimzadeh, Hadis, Pournasrollah, Mohammad, Gholinia Ahangar, Hemmat, Sadr Moharerpour, Sahar. (1405). Microalbuminuria in Children with Type 1 Diabetes Mellitus: 10-Year Data Analysis in Amirkola Children Hospital, Babol, Iran. سامانه مدیریت نشریات علمی, (), -. doi: 10.30476/ijns.2026.111137.1658
Faridokht Montazeri; Morteza Alijanpour; Hadis Ebrahimzadeh; Mohammad Pournasrollah; Hemmat Gholinia Ahangar; Sahar Sadr Moharerpour. "Microalbuminuria in Children with Type 1 Diabetes Mellitus: 10-Year Data Analysis in Amirkola Children Hospital, Babol, Iran". سامانه مدیریت نشریات علمی, , , 1405, -. doi: 10.30476/ijns.2026.111137.1658
Montazeri, Faridokht, Alijanpour, Morteza, Ebrahimzadeh, Hadis, Pournasrollah, Mohammad, Gholinia Ahangar, Hemmat, Sadr Moharerpour, Sahar. (1405). 'Microalbuminuria in Children with Type 1 Diabetes Mellitus: 10-Year Data Analysis in Amirkola Children Hospital, Babol, Iran', سامانه مدیریت نشریات علمی, (), pp. -. doi: 10.30476/ijns.2026.111137.1658
Montazeri, Faridokht, Alijanpour, Morteza, Ebrahimzadeh, Hadis, Pournasrollah, Mohammad, Gholinia Ahangar, Hemmat, Sadr Moharerpour, Sahar. Microalbuminuria in Children with Type 1 Diabetes Mellitus: 10-Year Data Analysis in Amirkola Children Hospital, Babol, Iran. سامانه مدیریت نشریات علمی, 1405; (): -. doi: 10.30476/ijns.2026.111137.1658

Microalbuminuria in Children with Type 1 Diabetes Mellitus: 10-Year Data Analysis in Amirkola Children Hospital, Babol, Iran

International Journal of Nutrition Sciences
مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 27 مرداد 1405    اصل مقاله (585.75 K)
نوع مقاله: Original Article
شناسه دیجیتال (DOI): 10.30476/ijns.2026.111137.1658
نویسندگان
Faridokht Montazeri1؛ Morteza Alijanpour2؛ Hadis Ebrahimzadeh3؛ Mohammad Pournasrollah3؛ Hemmat Gholinia Ahangar4؛ Sahar Sadr Moharerpour* 5
1Student Research Committee, Babol University of Medical Sciences, Babol, Iran
2Pediatric Endocrinology and Metabolism Department, Non-Communicable Pediatric Diseases Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran
3Clinical Research Development Unit of Amirkola Children’s Hospital, Babol University of Medical Sciences, Babol, Iran
4Health Research Institute, Babol University of Medical Sciences, Babol, Iran
5Pediatric Nephrology Department, Non-Communicable Pediatric Diseases Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran
چکیده
Background: Given the global rising incidence of type 1 diabetes (T1DM), this research was conducted to assess the demographic and laboratory findings of children with T1DM, based on the status of microalbuminuria.
Methods: This cross-sectional study compared the demographic and laboratory characteristics of all children under the age of 18 years who were diagnosed with T1DM at least for two years and have been referred to the referral Children’s Hospital in Babol, Iran. Age, sex, duration of diabetes, body mass index (BMI) and average of three measures of hemoglobin A1c were compared in two groups with and without microalbuminuria. Urinary albumin excretion of 30 to 300 mg/24 hours was considered as microalbuminuria.
Results: In the current study of 97 patients, 75 (77.3%) had microalbuminuria; while 22 (22.7%) did not experience microalbuminuria. There was no statistical difference in sex, age, BMI, duration and HbA1c distribution between patients with microalbuminuria and without microalbuminuria. In the univariate model, odds of microalbuminuria increase by 2.6 percent by each unit increased in HbA1c; however, this association was not statistically significant (odds ratio (OR): 1.026, confidence interval (CI) 95%: 0.779-1.325). No statistically significant association was also found between microalbuminuria status and sex, age, BMI, or duration.
Conclusion: Although the age, sex, duration of diabetes, BMI and hemoglobin A1c did not have statistically significant difference between the two groups, regular and periodic monitoring of glycemic control status and screening of protein excretion in urine, in order to identify early diabetic nephropathy is recommended in children with T1DM.
کلیدواژه‌ها
Diabetes mellitus؛ Children؛ Microalbuminuria؛ Kidney diseases؛ Iran
مراجع
  1. D'Souza D, Empringham J, Pechlivanoglou P, et al. Incidence of Diabetes in Children and Adolescents During the COVID-19 Pandemic: A Systematic Review and Meta-Analysis. JAMA Netw Open. 2023;6:e2321281. DOI:10.1001/jamanetworkopen.2023.21281.
  2. Masoumi SJ, Nekooeian AA, Tanideh N, et al. Effect of allium porrum on streptozotocin-induced diabetes mellitus hyperglycemia and insulin resistance in male Sprague Dawley rats. Onl J Vet Res. 2020;24:573-577. DOI: 10.5555/20203531172.
  3. Hashemipour M, Maracy M, Javanmard SH, Zamaneh F, Mostofizadeh N, Hovsepian S. Trends in incidence rates of childhood type 1 diabetes mellitus: A retrospective study in Isfahan province, Iran. J Diabetes Investig. 2023;14:376-86. DOI: 10.1111/jdi.13975. PMID: 36695001.
  4. Hosseini SE, Mehrabani D, Rezaei E. Effects of pomegranate juice on liver enzymes (ALT, ALP, AST) in diabetic and non-diabetic rats. J Anim Physiol Develop. 2014;24:59-64.
  5. Ng SM, Soni A. Ten-year review of trends in children with type 1 diabetes in England and Wales. World J Diabetes. 2023;14:1194-201. DOI: 10.4239/wjd.v14.i8.1194. PMID: 37664483.
  6. Bandarian F, Sharifnejad Tehrani Y, Peimani M, et al. National and sub-national burden and trend of type 1 diabetes in 31 provinces of Iran, 1990-2019. Sci Rep. 2023;13:4210. DOI: 10.1038/s41598-023-31096-8. PMID: 36918650.
  7. Chiang JL, Maahs DM, Garvey KC, et al. Type 1 Diabetes in Children and Adolescents: A Position Statement by the American Diabetes Association. Diabetes Care. 2018;41:2026-44. DOI: 10.2337/dci18-0023. PMID: 30093549.
  8. Almasi-Hashiani A, Rajaeefard Ar, Hassanzade J, et al. Graft Survival Rate In Pediatric Renal Transplantation: A Single Center Experience. Pak J Med Sci. 2012;28:1-6.
  9. Sharifzadeh M, Esmaeili-Bandboni A, Emami MR, et al. Protective Effect of Alginate Extraction of Brown Algae on MicroRNAs in Type 1 Diabetes of Rats. Int J Nutr Sci. 2024;9:318-324. DOI: 10.30476/ijns.2024.102136.1314.
  10. Mamilly L, Mastrandrea LD, Mosquera Vasquez C, et al. Evidence of Early Diabetic Nephropathy in Pediatric Type 1 Diabetes. Front Endocrinol (Lausanne). 2021;12:669954. DOI: 10.3389/fendo.2021.669954. PMID: 33995287.
  11. Ambarsari CG, Tambunan T, Pardede SO, et al. Role of dipstick albuminuria in progression of paediatric chronic kidney disease. J Pak Med Assoc. 2021;71:S103-S106. PMID: 33785952.
  12. Sheikhani Shahin H, Koushkie Jaromi M, Kardeh E, et al. The effect of aerobic exercise on bone mineral density and bone mineral content in female athlete patients following kidney transplantation in Shiraz, southern Iran. World Appl Sci J. 2013;27:23-27. DOI: 10.5829/idosi.wasj.2013.27.01.7566.
  13. Prasad RM, Tikaria R. Microalbuminuria. In: Stat Pearls [Internet]. Treasure Island (FL): StatPearls Publishing; Jan 2021. Available from: https://www.ncbi.nlm.nih.gov/books/NBK563255/. 2020. Updated 2020 Sep 27.
  14. Salahshornezhad S, Sabet Ghadam O, Akbarzadeh M, et al. Advanced Glycosylation End Products: Effects in Chronic Kidney Disease and Related Disorders.
  1. Cho H, Kim JH. Prevalence of microalbuminuria and its associated cardiometabolic risk factors in Korean youth: Data from the Korea National Health and Nutrition Examination Survey. PLoS One. 2017;12:e0178716-e. DOI: 10.1371/journal.pone.0178716. PMID: 28575100.
  2. Bartz SK, Caldas MC, Tomsa A, et al. Urine Albumin-to-Creatinine Ratio: A Marker of Early Endothelial Dysfunction in Youth. J Clin Endocrinol Metab. 2015;100:3393-9. DOI: 10.1210/JC.2015-2230. PMID: 26176802.
  3. Zabeen B, Nahar J, Islam N, et al. Risk Factors Associated with Microalbuminuria in Children and Adolescents with Diabetes in Bangladesh. Indian J Endocrinol Metab. 2018;22:85-8. DOI: 10.4103/ijem.IJEM_269_17. PMID: 29535943.
  4. Jeddi M, Torabi E. The Relationship between Zinc, Glycemic Control and Microvascular Complications of Diabetes Mellitus.
  1. Ansar MM, ShahrokhiRad R, Lebady MK. Risk Factors of Microalbuminuria and Macroalbuminuria in Type 2 Diabetic Patients in North of Iran - Rasht. Nephro-Urol Mon. 2017;9:e40031. DOI: 10.5812/numonthly.40031.
  2. Razavi Z, Momtaz E, Sahari S. Frequency of microalbuminuria in type 1 diabetic children. Iran J Pediatrics. 2009;19:404-8. (Persian).
  3. Khalili M, Sadeghi-Bojd S, Teimouri A, et al. Urine Microalbuminuria in Obese Comparing with Healthy Children. gums-cjhr. 2020;5:8-11.
  4. ElSayed NA, Aleppo G, Aroda VR, Bannuru RR, Brown FM, Bruemmer D, et al. 2. Classification and Diagnosis of Diabetes: Standards of Care in Diabetes-2023. Diabetes Care. 2023;46:S19-S40. DOI: 10.2337/dc23-S002. PMID: 36507649.
  5. Yang CC, Lin CH, Wang NK, et al. Risk Factors Associated With the Development of Nephropathy 10 Years After Diagnosis in Taiwanese Children With Juvenile-Onset Type 1 Diabetes—A Cohort Study From the CGJDES. Front Endocrinol. 2018;9:429. DOI: 10.3389/fendo.2018.00429. PMID: 30123184.
  6. Bhattarai T, Pandey A, Parajuli S, et al. Microalbuminuria among Patients with Diabetes Mellitus Visiting the Department of Nephrology in a Tertiary Care Centre: A Descriptive Cross-sectional Study. JNMA J Nepal Med Assoc. 2023;61:596-8 DOI: 1031729/jnma8214. PMID: 40802713.
  7. ElSayed NA, Aleppo G, Aroda VR, et al. 14. Children and Adolescents: Standards of Care in Diabetes-2023. Diabetes Care. 2023;46:S230-S53. DOI: 10.2337/dc23-S014. PMID: 36507640.
  8. Mohammed MM, Alnajim EK, Hussein MAA, et al. RISK FACTORS FOR DIABETIC NEPHROPATHY IN DIABETES MELLITUS TYPE 1. Wiad Lek. 2023;76:145-54. DOI: 10.36740/WLek202301120. PMID: 36883503.
  9. Nguyen A, Khafagy R, Gao Y, et al. Association Between Obesity and Chronic Kidney Disease: Multivariable Mendelian Randomization Analysis and Observational Data From a Bariatric Surgery Cohort. Diabetes. 2023;72:496-510. DOI: 10.2337/db22-0696. PMID: 36657976.
  10. Ciężki S, Kurpiewska E, Bossowski A, et al. Multi-Faceted Influence of Obesity on Type 1 Diabetes in Children - From Disease Pathogenesis to Complications. Front Endocrinol (Lausanne). 2022;13:890833. DOI: 10.3389/fendo.2022.890833. PMID: 35784568.
  11. Karguppikar M, Oza C, Shah N, et al. Prevalence of nephropathy in Indian children and youth with type 1 diabetes mellitus. J Pediatr Endocrinol Metab. 2022;35:585-92. DOI: 10.1515/jpem-2021-0644. PMID: 35304981.
  12. Rivetti G, Hursh BE, Miraglia del Giudice E, et al. Acute and chronic kidney complications in children with type 1 diabetes mellitus. Pediatr Nephrol. 2023;38:1449-58. DOI: 10.1007/s00467-022-05689-w. PMID: 35896816.
  13. Parsa F, Hoseini SE, Mehrabani D, et al. The effect of Cannabis sativa on memory, apoptotic genes and inflammatory cytokines in rat. Acad J Health Sci Med Balear. 2021;36:96-101.
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