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Nili, Fatemeh, Parviz, Sara, Jalaeefar, Amirmohsen, Mousavi, Seyedeh Zahra, Tayebi, Nastaran. (1405). Post-Radiation Vaginal Angiosarcoma: A Case Report. سامانه مدیریت نشریات علمی, 17(4), 379-384. doi: 10.30476/mejc.2026.106736.2268
Fatemeh Nili; Sara Parviz; Amirmohsen Jalaeefar; Seyedeh Zahra Mousavi; Nastaran Tayebi. "Post-Radiation Vaginal Angiosarcoma: A Case Report". سامانه مدیریت نشریات علمی, 17, 4, 1405, 379-384. doi: 10.30476/mejc.2026.106736.2268
Nili, Fatemeh, Parviz, Sara, Jalaeefar, Amirmohsen, Mousavi, Seyedeh Zahra, Tayebi, Nastaran. (1405). 'Post-Radiation Vaginal Angiosarcoma: A Case Report', سامانه مدیریت نشریات علمی, 17(4), pp. 379-384. doi: 10.30476/mejc.2026.106736.2268
Nili, Fatemeh, Parviz, Sara, Jalaeefar, Amirmohsen, Mousavi, Seyedeh Zahra, Tayebi, Nastaran. Post-Radiation Vaginal Angiosarcoma: A Case Report. سامانه مدیریت نشریات علمی, 1405; 17(4): 379-384. doi: 10.30476/mejc.2026.106736.2268

Post-Radiation Vaginal Angiosarcoma: A Case Report

Middle East Journal of Cancer
مقاله 21، دوره 17، شماره 4 - شماره پیاپی 68، دی 2026، صفحه 379-384    اصل مقاله (2.51 M)
نوع مقاله: Case Report(s)
شناسه دیجیتال (DOI): 10.30476/mejc.2026.106736.2268
نویسندگان
Fatemeh Nili1؛ Sara Parviz2؛ Amirmohsen Jalaeefar3؛ Seyedeh Zahra Mousavi3؛ Nastaran Tayebi* 4
1Department of Pathology, Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
2Department of Radiology, Medical Imaging Center, Imam Khomeini Hospital Complex (IKHC), Muscloskeletal Imaging Research Center (MIRC), Tehran University of Medical Sciences, Tehran, Iran
3Department of Oncosurgery, Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
4Department of Pathology, Yas Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
چکیده
Angiosarcoma, an uncommon sarcoma, comprises only 1% of all soft tissue sarcomas. In the female genital tract, fewer than 70 cases have been reported previously. Due to rarity, there is no consensus about their treatment, especially in female genital tract. Herein, a 56-year-old woman, who was a known case of human papillomavirus-associated endocervical mucinous adenocarcinoma, stage Ib2 was presented with vaginal bleeding. The patient underwent total abdominal hysterectomy, bilateral salpingo-oophorectomy, lymph node dissection and radiotherapy 15 years ago. Pelvic magnetic resonance imaging before and after contrast administration showed an area of mass-like thickening in the left side of vaginal cuff. A core needle biopsy was performed and demonstrated anastomosing vascular channels with atypical endothelial cell lining. 12 months after anterior pelvic exenteration, the patient remains in good condition with no evidence of recurrence or metastasis, and the ileal conduit is functioning well. Post-radiation vaginal angiosarcoma is a rare complication of female genital tract tumors that should be considered in differential diagnosis of late onset tumors in this region. Primary or adjuvant chemotherapy should be considered for treatment of these patients.

تازه های تحقیق

Fatemeh Nili (google scholar)

 

کلیدواژه‌ها
Radiation؛ Angiosarcoma؛ Vagina؛ Case report
مراجع
  1. Cao J, Wang J, He C, Fang M. Angiosarcoma: a review of diagnosis and current treatment. Am J Cancer Res. 2019;9(11):2303-13. PMID: 31815036; PMCID: PMC6895451.
  2. Ike E, Mai JZ, Sargen MR, Schonfeld SJ, Cahoon EK. Ambient UV radiation is associated with cutaneous angiosarcoma incidence in the United States, 1992 to 2020. J Am Acad Dermatol. 2024;91(1):102-4. doi: 10.1016/j.jaad.2024.01.084. PMID: 38432461; PMCID: PMC11193604.
  3. Shah S, Rosa M. Radiation-associated angiosarcoma of the breast: Clinical and pathologic features. Arch Pathol Lab Med. 2016;140(5):477-81. doi: 10.5858/arpa.2014-0581-RS. PMID: 27128306.
  4. Kruse AJ, Sep S, Slangen BF, Vandevijver NM, Van Gorp T, Kruitwagen RF, et al. Angiosarcomas of primary gynecologic origin: a clinicopathologic review and quantitative analysis of survival. Int J Gynecol Cancer. 2014;24(1):4-12. doi: 10.1097/IGC.0000000000000020. PMID: 24257655.
  5. Chinczewski L, Taube ET, Feldhaus FW, Dröge LA, Chekerov R, Muallem MZ, et al. Angiosarcomas of primary gynecologic origin: a case series and review of the literature. Anticancer Res. 2020;40(10):5743-50. doi: 10.21873/anticanres.14590. PMID: 32988901.
  6. Betancourt R, Randall C, Kuan-Celarier A, West L, Soper J, Bookhout C. Post-radiation angiosarcoma of the uterine cervix. Gynecol Oncol Rep. 2019;29:13-5. doi: 10.1016/j.gore.2019.05.005. PMID: 31193499; PMCID: PMC6535627.
  7. Ohayi SA, Ezugwu EC, Aderibigbe AS, Udeh EI. Angiosarcoma of the cervix: a case and literature review. Niger J Med. 2013;22(4):362-4. PMID: 24283102.
  8. Ahmad M, Warren L, Ingyin H, Naumaan A, Da Silva AF. Primary vaginal epithelioid angiosarcoma: a case report and literature review of a rare neoplasm. 2023;15(5):e39258. doi: 10.7759/cureus.39258. PMID: 37228354; PMCID: PMC10205154.
  9. Rutland CD, Bean GR, Charville GW. Contemporary diagnostic approach to atypical vascular lesion and angiosarcoma. Semin Diagn Pathol. 2023;40(6):426-37.
  10. Gagnier JJ, Kienle G, Altman DG, Moher D, Sox H, Riley D, et al. The CARE guidelines: consensus-based clinical case reporting guideline development. Glob Adv Health Med. 2013;2(5):38-43. doi: 10.7453/gahmj.2013.008. PMID: 24416692; PMCID: PMC3833570.
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