LinkedIn

 آمار

تعداد نشریات21
تعداد شماره‌ها1,282
تعداد مقالات11,718
تعداد مشاهده مقاله82,660,967
تعداد دریافت فایل اصل مقاله121,561,019
Torabi-Jahromi, Alireza, Rastgoftar, Zahra, Zeinali-Rafsanjani, Banafsheh, Dousty, Behnam, Alizadeh, Forough, Shamsodidni, Mohammad Bagher, Pishdad, Parisa. (1405). Fatigue Prevalence and its Association with MRI Findings in Multiple Sclerosis: A Cross-Sectional Study. سامانه مدیریت نشریات علمی, (), -.
Alireza Torabi-Jahromi; Zahra Rastgoftar; Banafsheh Zeinali-Rafsanjani; Behnam Dousty; Forough Alizadeh; Mohammad Bagher Shamsodidni; Parisa Pishdad. "Fatigue Prevalence and its Association with MRI Findings in Multiple Sclerosis: A Cross-Sectional Study". سامانه مدیریت نشریات علمی, , , 1405, -.
Torabi-Jahromi, Alireza, Rastgoftar, Zahra, Zeinali-Rafsanjani, Banafsheh, Dousty, Behnam, Alizadeh, Forough, Shamsodidni, Mohammad Bagher, Pishdad, Parisa. (1405). 'Fatigue Prevalence and its Association with MRI Findings in Multiple Sclerosis: A Cross-Sectional Study', سامانه مدیریت نشریات علمی, (), pp. -.
Torabi-Jahromi, Alireza, Rastgoftar, Zahra, Zeinali-Rafsanjani, Banafsheh, Dousty, Behnam, Alizadeh, Forough, Shamsodidni, Mohammad Bagher, Pishdad, Parisa. Fatigue Prevalence and its Association with MRI Findings in Multiple Sclerosis: A Cross-Sectional Study. سامانه مدیریت نشریات علمی, 1405; (): -.

Fatigue Prevalence and its Association with MRI Findings in Multiple Sclerosis: A Cross-Sectional Study

Journal of Biomedical Physics and Engineering
مقالات آماده انتشار، اصلاح شده برای چاپ، انتشار آنلاین از تاریخ 17 تیر 1405    اصل مقاله (749.69 K)
نوع مقاله: Original Research
نویسندگان
Alireza Torabi-Jahromi1، 2؛ Zahra Rastgoftar2، 3؛ Banafsheh Zeinali-Rafsanjani1؛ Behnam Dousty1، 2؛ Forough Alizadeh1؛ Mohammad Bagher Shamsodidni1؛ Parisa Pishdad* 1
1Medical Imaging Research Center, Department of Radiology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
2Student Research Committee, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
3Otolaryngology Research Center, Department of Otolaryngology, Shiraz University of Medical Sciences, Shiraz, Iran
چکیده
Background: Fatigue is a common and disabling symptom in Multiple Sclerosis (MS), yet its underlying mechanisms and neuroimaging findings remain unclear, particularly in understudied populations such as Iran.
Objective: This study aimed to determine the prevalence of fatigue in MS compared with healthy controls and to explore its associations with brain and spinal cord Magnetic Resonance Imaging (MRI) findings.
Material and Methods: In this cross-sectional study, 100 MS patients and 100 age- and sex-matched controls were enrolled. Fatigue was assessed using the Fatigue Assessment Scale (FAS). MRI data for MS patients, including lesion counts and volumetric measures, were analyzed using the volBrain platform. Statistical analyses (Mann-Whitney U, Kruskal-Wallis, and Spearman’s correlation) were performed using SPSS.
Results: Significant fatigue (FAS ≥22) was reported by 92% of MS patients (mean =29.55±4.41) versus 62% of controls. In MS patients, fatigue correlated positively with total lesion count (rho=0.203, P=0.043) and juxtacortical lesion count. No significant associations were found with brain volume, spinal lesions, or demographic variables. Cervical plaques were present in 85% of patients, but were not significantly linked to fatigue. 
Conclusion: Fatigue is highly prevalent and more severe in MS patients than in healthy individuals, correlating with total and juxtacortical lesion burden. These findings suggest a role for lesion load in MS-related fatigue and underscore the need for longitudinal and functional imaging studies to clarify its mechanisms and guide targeted interventions.
کلیدواژه‌ها
Multiple Sclerosis؛ Fatigue؛ Magnetic Resonance Imaging؛ Lesion Burden, Brain
آمار
تعداد مشاهده مقاله: 2
تعداد دریافت فایل اصل مقاله: 1


سامانه مدیریت نشریات علمی. قدرت گرفته از سیناوب