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Mohit, Mohsen, Hosseini, Sayedeh Zahra, Ravanbod, Mohammadreza, Hosseini, Seyed Vahid, Hejazi, Najmeh. (1405). Association of Dietary Patterns and the Odds of Colorectal Cancer in a Sample of the Population in Southern Iran: An Observational Case-Control Study. سامانه مدیریت نشریات علمی, (), -. doi: 10.30476/mejc.2026.110553.2401
Mohsen Mohit; Sayedeh Zahra Hosseini; Mohammadreza Ravanbod; Seyed Vahid Hosseini; Najmeh Hejazi. "Association of Dietary Patterns and the Odds of Colorectal Cancer in a Sample of the Population in Southern Iran: An Observational Case-Control Study". سامانه مدیریت نشریات علمی, , , 1405, -. doi: 10.30476/mejc.2026.110553.2401
Mohit, Mohsen, Hosseini, Sayedeh Zahra, Ravanbod, Mohammadreza, Hosseini, Seyed Vahid, Hejazi, Najmeh. (1405). 'Association of Dietary Patterns and the Odds of Colorectal Cancer in a Sample of the Population in Southern Iran: An Observational Case-Control Study', سامانه مدیریت نشریات علمی, (), pp. -. doi: 10.30476/mejc.2026.110553.2401
Mohit, Mohsen, Hosseini, Sayedeh Zahra, Ravanbod, Mohammadreza, Hosseini, Seyed Vahid, Hejazi, Najmeh. Association of Dietary Patterns and the Odds of Colorectal Cancer in a Sample of the Population in Southern Iran: An Observational Case-Control Study. سامانه مدیریت نشریات علمی, 1405; (): -. doi: 10.30476/mejc.2026.110553.2401

Association of Dietary Patterns and the Odds of Colorectal Cancer in a Sample of the Population in Southern Iran: An Observational Case-Control Study

Middle East Journal of Cancer
مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 11 دی 1405    اصل مقاله (349.77 K)
نوع مقاله: Original Article(s)
شناسه دیجیتال (DOI): 10.30476/mejc.2026.110553.2401
نویسندگان
Mohsen Mohit* 1؛ Sayedeh Zahra Hosseini2؛ Mohammadreza Ravanbod3؛ Seyed Vahid Hosseini4؛ Najmeh Hejazi5
1Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran, Department of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran
2Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
3Department of Hematology and Medical Oncology, Shiraz University of Medical Sciences, Shiraz, Iran
4Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
5Department of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran
چکیده
Background: Colorectal cancer is the second leading cause of cancer-related deaths for both men and women. This study aimed to explore the association between dietary patterns and the odds of colorectal cancer in an Iranian adult population.
Method: This observational case-control study was conducted at three educational and therapeutic centers affiliated with Shiraz University of Medical Sciences. A total of 207 participants were enrolled in the study, comprising 103 individuals with colorectal cancer (case group) and 104 individuals without colorectal cancer (control group). The participants' dietary intake was assessed using a valid and reliable food frequency questionnaire comprising 117 items. Dietary patterns were analyzed using principal component analysis, and their relationship with colorectal cancer was investigated using logistic regression, reporting odds ratios with 95% confidence intervals.
Results: Two main dietary patterns were identified in this study; the high-fiber pattern (HFP) and the unhealthy pattern (UHP). These patterns explained 11.46% and 11.98% of the total variance, respectively. An HFP was significantly associated with  reduced odds of colorectal cancer in both the crude and adjusted models. Conversely, adherence to a UHP was significantly associated with an increased risk of colorectal cancer in both crude and adjusted models.
Conclusion: These findings suggest that adherence to an HFP is associated with a reduced risk of colorectal cancer, whereas adherence to a UHP is associated with an increased risk. Overall, these results underscore the importance of modifying dietary habits as a strategic approach to the prevention of colorectal cancer among the adult population in Iran.

تازه های تحقیق

Najmeh Hejazi (google scholar)

کلیدواژه‌ها
Dietary pattern؛ Colorectal neoplasms؛ Dietary fiber؛ Fast food
مراجع
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