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In Which form of Inflammatory bowel Disease Is Reduction in Quality of Life more Common: Ulcerative Colitis or Crohn’s Disease? | ||
| Iranian Journal of Colorectal Research | ||
| مقاله 4، دوره 13، شماره 4، اسفند 2025 اصل مقاله (501.15 K) | ||
| نوع مقاله: Research/Original Article | ||
| شناسه دیجیتال (DOI): 10.30476/acrr.2026.108827.1268 | ||
| نویسندگان | ||
| seyedehfatemeh rasouli* 1؛ kamran ebrahimizad2 | ||
| 1Independent Researcher, Orlando, FL, USA | ||
| 2Independent Researcher, Tehran, Iran | ||
| چکیده | ||
| Background: Despite differences in histopathological features and prognostic characteristics between ulcerative colitis and Crohn’s disease, the difference in the patients’ quality of life with these two conditions remains unclear. Our goal was to evaluate the differences in various aspects of the quality of life with these two forms of inflammatory bowel disease (IBD). Methods: This cross-sectional study was performed on patients with a confirmed diagnosis of IBD. The sample comprised 120 patients with ulcerative colitis and 120 with Crohn’s disease, all of whom had been diagnosed for at least six months prior to the study. Baseline characteristics were collected by interviewing the patients. Quality of life was assessed using the Inflammatory Bowel Disease Questionnaire (IBDQ-32). Results: Comparing different components of quality of life between the patients with ulcerative colitis and Crohn’s disease showed a significantly higher mean score for emotional and social functioning; however, no difference was observed in the mean scores for systemic symptoms and bowel symptoms between the two groups. Overall, the comparison of general quality of life score between the groups with ulcerative colitis and Crohn’s disease showed a significantly higher mean score for the latter group, even after adjusting baseline parameters. The overall quality of life score was significantly higher in patients with Crohn’s disease compared to ulcerative colitis (P<0.001), and this difference remained significant after multivariable adjustment (P<0.001). Conclusion: More severe disturbances in various aspects of quality of life should be expected in patients with ulcerative colitis compared to those with Crohn’s disease. This difference remained significant after adjustment for baseline characteristics. Greater attention to psychosocial support in patients with ulcerative colitis may help improve quality of life. | ||
تازه های تحقیق | ||
Seyedehfatemeh Rasouli (Google Scholar) | ||
| کلیدواژهها | ||
| Inflammatory Bowel Diseases؛ Crohn Disease؛ Quality of Life؛ Ulcerative Colitis؛ Patient Reported Outcome Measures | ||
| مراجع | ||
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