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Sattarian, Ali, Akbarzadeh Morshedi, Minoo. (1405). Dietary and Topical Antioxidants in Skin Cancer: A Narrative Review on Prevention, Treatment, and Dermatological Care in Patients and Survivors. سامانه مدیریت نشریات علمی, 11(2), 227-241. doi: 10.30476/ijns.2026.107353.1494
Ali Sattarian; Minoo Akbarzadeh Morshedi. "Dietary and Topical Antioxidants in Skin Cancer: A Narrative Review on Prevention, Treatment, and Dermatological Care in Patients and Survivors". سامانه مدیریت نشریات علمی, 11, 2, 1405, 227-241. doi: 10.30476/ijns.2026.107353.1494
Sattarian, Ali, Akbarzadeh Morshedi, Minoo. (1405). 'Dietary and Topical Antioxidants in Skin Cancer: A Narrative Review on Prevention, Treatment, and Dermatological Care in Patients and Survivors', سامانه مدیریت نشریات علمی, 11(2), pp. 227-241. doi: 10.30476/ijns.2026.107353.1494
Sattarian, Ali, Akbarzadeh Morshedi, Minoo. Dietary and Topical Antioxidants in Skin Cancer: A Narrative Review on Prevention, Treatment, and Dermatological Care in Patients and Survivors. سامانه مدیریت نشریات علمی, 1405; 11(2): 227-241. doi: 10.30476/ijns.2026.107353.1494

Dietary and Topical Antioxidants in Skin Cancer: A Narrative Review on Prevention, Treatment, and Dermatological Care in Patients and Survivors

International Journal of Nutrition Sciences
مقاله 5، دوره 11، شماره 2، شهریور 2026، صفحه 227-241    اصل مقاله (493.93 K)
نوع مقاله: Review Article
شناسه دیجیتال (DOI): 10.30476/ijns.2026.107353.1494
نویسندگان
Ali Sattarian1؛ Minoo Akbarzadeh Morshedi* 2
1School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
2Research Center for Biochemistry and Nutrition in Metabolic Diseases, Institute for Basic Science, Kashan University of Medical Sciences, Ravand, Kashan, Iran
چکیده
Skin cancer remains a significant global health challenge, with ultraviolet (UV) radiation-induced oxidative stress playing a pivotal role in the pathogenesis. Antioxidants exhibit potent free radical scavenging properties that mitigate UV-induced DNA damage and inflammatory responses. This narrative review critically examined the role of dietary
and topical antioxidants in the prevention, treatment, and dermatological care of skin cancer. Here, we conducted a comprehensive search across major medical databases for all research types. The search employed the keywords of antioxidants, oxidative stress, skin cancer, skin neoplasms and skin care. Dietary antioxidants were shown to be associated with reduced incidence and progression of various skin cancers, highlighting the importance of nutritional strategies in primary prevention. Topical antioxidants, formulated in dermatological preparations, offer localized protection by enhancing the endogenous defense mechanisms and improving repair processes of the skin post-UV exposure. In conclusion, the adjunctive use of antioxidants may improve treatment outcomes and reduce adverse effects of conventional therapies. In skin cancer survivors, sustained antioxidant therapy may contribute to improved skin health, reduced recurrence risk, and enhanced quality of life. Despite promising findings, heterogeneity in study designs and antioxidant formulations necessitates further researches to establish standardized guidelines.

تازه های تحقیق

Minoo Akbarzadeh Morshedi (Google Scholar)

کلیدواژه‌ها
Antioxidant؛ Oxidative stress؛ Skin cancer؛ Skin neoplasms؛ Cancer survivors
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