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Alqalamchi, Shahd, Saeed, Ghassan Thabet. (1405). Analysis of Insulin Resistance Markers and Lipid Profile in Patients in Baghdad, Iraq. سامانه مدیریت نشریات علمی, 11(2), 242-247. doi: 10.30476/ijns.2026.106159.1429
Shahd M. Alqalamchi; Ghassan Thabet Saeed. "Analysis of Insulin Resistance Markers and Lipid Profile in Patients in Baghdad, Iraq". سامانه مدیریت نشریات علمی, 11, 2, 1405, 242-247. doi: 10.30476/ijns.2026.106159.1429
Alqalamchi, Shahd, Saeed, Ghassan Thabet. (1405). 'Analysis of Insulin Resistance Markers and Lipid Profile in Patients in Baghdad, Iraq', سامانه مدیریت نشریات علمی, 11(2), pp. 242-247. doi: 10.30476/ijns.2026.106159.1429
Alqalamchi, Shahd, Saeed, Ghassan Thabet. Analysis of Insulin Resistance Markers and Lipid Profile in Patients in Baghdad, Iraq. سامانه مدیریت نشریات علمی, 1405; 11(2): 242-247. doi: 10.30476/ijns.2026.106159.1429

Analysis of Insulin Resistance Markers and Lipid Profile in Patients in Baghdad, Iraq

International Journal of Nutrition Sciences
مقاله 6، دوره 11، شماره 2، شهریور 2026، صفحه 242-247    اصل مقاله (370.42 K)
نوع مقاله: Original Article
شناسه دیجیتال (DOI): 10.30476/ijns.2026.106159.1429
نویسندگان
Shahd M. Alqalamchi؛ Ghassan Thabet Saeed*
Department of Physiology, College of Medicine/ University of Baghdad, Baghdad, Iraq
چکیده
Background: Insulin resistance (IR) is a detrimental common condition related to type 2 diabetes mellitus and different metabolic diseases. The common indices are the homeostasis model assessment of insulin resistance (HOMA-IR) and triglyceride glucose (TyG) index. This study analyzed IR markers and lipid profile in patients in Baghdad, Iraq.
Methods: A cross-sectional study from March 7 2024 to June 1st 2024 was performed at Nutrition and Obesity Center in Al-Kindy Hospital, Baghdad, Iraq enrolling 100 participants (81 females and 19 males) aged between 18-60 years. They were categorized into obese and non-obese groups based on their BMI values. BMI, fasting blood glucose, fasting insulin and lipid profile (total cholesterol, triglycerides, LDL-C, and HDL-C) and HbA1C were determined and analyzed.
Results: HOMA-IR index detected 38% of IR individuals, while TyG index verified 51%. BMI was shown to be correlated too (p=0.0001, p=0.033, respectively). For lipid profile, LDL-C and total cholesterol were inversely related to HOMA-IR index (p=0.048, p=0.163, respectively). HDL-C had inverse relationship with HOMA-IR (p=0.014), and triglyceride had a positive correlation with HOMA-IR (p=0.190). TyG revealed a positive correlation with total cholesterol and triglyceride (p=0.0006, p=0.0001, respectively). The correlation between TyG index and LDL was positive, and forTyG and HDL was negative (p=0.105, p=0.179, respectively).
Conclusion: TyG index was superior to HOMA-IR with a stronger positive correlation to the BMI marker too. Lipid profile revealed a weak relationship with HOMA-IR ant TyG indices.
کلیدواژه‌ها
Insulin resistance؛ Triglyceride glucose index؛ HOMA-IR index؛ BMI؛ Lipid profile
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