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Afshari, Maryam, Sharifi, Mohammad Hossein, Molavi Vardanjani, Hossein, Nikmanesh, Amirreza. (1405). Adherence to Medication, Mediterranean Diet, and Physical Activity and Their Predictors in Heart Failure Patients. سامانه مدیریت نشریات علمی, 51(4), 236-247. doi: 10.30476/ijms.2025.106829.4113
Maryam Afshari; Mohammad Hossein Sharifi; Hossein Molavi Vardanjani; Amirreza Nikmanesh. "Adherence to Medication, Mediterranean Diet, and Physical Activity and Their Predictors in Heart Failure Patients". سامانه مدیریت نشریات علمی, 51, 4, 1405, 236-247. doi: 10.30476/ijms.2025.106829.4113
Afshari, Maryam, Sharifi, Mohammad Hossein, Molavi Vardanjani, Hossein, Nikmanesh, Amirreza. (1405). 'Adherence to Medication, Mediterranean Diet, and Physical Activity and Their Predictors in Heart Failure Patients', سامانه مدیریت نشریات علمی, 51(4), pp. 236-247. doi: 10.30476/ijms.2025.106829.4113
Afshari, Maryam, Sharifi, Mohammad Hossein, Molavi Vardanjani, Hossein, Nikmanesh, Amirreza. Adherence to Medication, Mediterranean Diet, and Physical Activity and Their Predictors in Heart Failure Patients. سامانه مدیریت نشریات علمی, 1405; 51(4): 236-247. doi: 10.30476/ijms.2025.106829.4113

Adherence to Medication, Mediterranean Diet, and Physical Activity and Their Predictors in Heart Failure Patients

Iranian Journal of Medical Sciences
مقاله 2، دوره 51، شماره 4، تیر 2026، صفحه 236-247    اصل مقاله (594.06 K)
نوع مقاله: Original Article(s)
شناسه دیجیتال (DOI): 10.30476/ijms.2025.106829.4113
نویسندگان
Maryam Afshari1؛ Mohammad Hossein Sharifi2؛ Hossein Molavi Vardanjani3؛ Amirreza Nikmanesh4
1Department of MPH, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
2Research Center for Traditional Medicine and History of Medicine, Non-Communicable Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
3Department of MPH, School of Medicine, Research Center for Traditional Medicine and History of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
4School of Medicine, Fasa University of Medical Sciences, Fasa, Iran
چکیده
Background: Adherence to prescribed medications, a healthy diet, and regular physical activity is essential for the optimal management of heart failure (HF). Therefore, the present study aimed to determine the level of adherence to medications, the Mediterranean diet (MD), and physical activity, and to identify their correlations.
Methods: In this cross-sectional study, HF patients who were hospitalized from March to November 2022 were enrolled. Medication adherence, the MD, and physical activity were assessed using the 8-item Morisky medication adherence scale, the 14-item MD adherence Screener (MEDAS), and the International Physical Activity Questionnaire (IPAQ), respectively. Univariate analyses were conducted using the Chi square and Kruskal–Wallis tests. Ordinal logistic regression was applied to examine factors associated with adherence levels. Data were analyzed using Stata software (version 17), and P<0.05 was considered statistically significant.
Results: Data from 320 patients were analyzed. Suboptimal adherence was observed in 97 (30.3%), 88 (27.5%), and 224 (70%) 
of participants for medication, MD, and physical activity, respectively, and was linked to lower left ventricular ejection fraction. Multivariable analysis revealed that lower medication adherence was associated with older age, tobacco use, and a higher number of comorbidities. Reduced MD adherence was related to a higher body mass index (BMI), the presence of comorbidities, and a history of cerebrovascular accident or myocardial infarction. Lower physical activity levels were associated with older age, a higher BMI, a greater number of comorbidities, and a lower socioeconomic status.
Conclusion: In HF patients, nonadherence to medication, the MD, and physical activity were common and associated with poorer cardiac function and a greater comorbid burden. These findings underscore the importance of a multidisciplinary approach to enhance adherence and improve overall patient outcomes.

تازه های تحقیق

Maryam Afshari (Google Scholar) 
Mohammad Hossein Sharifi (Google Scholar) 

کلیدواژه‌ها
Heart failure؛ Medication adherence؛ Diet, mediterranean؛ Exercise
مراجع
  1. Groenewegen A, Rutten FH, Mosterd A, Hoes AW. Epidemiology of heart failure. Eur J Heart Fail. 2020;22:1342-56. doi: 10.1002/ejhf.1858. PubMed PMID: 32483830; PubMed Central PMCID: PMC7540043.
  2. James SL, Abate D, Abate KH, Abay SM, Abbafati C, Abbasi N, et al. Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018;392:1789-858. doi: 10.1016/s0140-6736(18)32279-7. PubMed PMID: 30496104; PubMed Central PMCID: PMC6227754.
  3. Mirahmadizadeh A, Khorshidsavar H, Seif M, Sharifi MH. Adherence to Medication, Diet and Physical Activity and the Associated Factors Amongst Patients with Type 2 Diabetes. Diabetes Ther. 2020;11:479-94. doi: 10.1007/s13300-019-00750-8. PubMed PMID: 31916213; PubMed Central PMCID: PMC6995790.
  4. Metra M, Teerlink JR. Heart failure. Lancet. 2017;390:1981-95. doi: 10.1016/s0140-6736(17)31071-1. PubMed PMID: 28460827.
  5. Ruppar TM, Cooper PS, Mehr DR, Delgado JM, Dunbar-Jacob JM. Medication Adherence Interventions Improve Heart Failure Mortality and Readmission Rates: Systematic Review and Meta-Analysis of Controlled Trials. J Am Heart Assoc. 2016;5. doi: 10.1161/jaha.115.002606. PubMed PMID: 27317347; PubMed Central PMCID: PMC4937243.
  6. Jarab AS, Al-Qerem WA, Hamam HW, Alzoubi KH, Abu Heshmeh SR, Mukattash TL, et al. Medication Adherence and Its Associated Factors Among Outpatients with Heart Failure. Patient Prefer Adherence. 2023;17:1209-20. doi: 10.2147/ppa.s410371. PubMed PMID: 37187575; PubMed Central PMCID: PMC10178996.
  7. Yeong L J, Ogston SA, Hall C, Heather D, Elder DH, Choy AM, et al. 009 Adherence to Heart Failure Therapy and Outcome: A Population Based Study. Heart. 2013;99:A12-A. doi: 10.1136/heartjnl-2013-304019.9.
  8. Amininasab SS, Lolaty HA, Moosazadeh M, Shafipour V. Medication adherence and its predictors among patients with heart failure. Nursing and Midwifery Studies. 2018;7:81-6. doi: 10.4103/nms.nms_9_17.
  9. Martínez-González MA, Gea A, Ruiz-Canela M. The Mediterranean Diet and Cardiovascular Health. Circ Res. 2019;124:779-98. doi: 10.1161/circresaha.118.313348. PubMed PMID: 30817261.
  10. Miró Ò, Estruch R, Martín-Sánchez FJ, Gil V, Jacob J, Herrero-Puente P, et al. Adherence to Mediterranean Diet and All-Cause Mortality After an Episode of Acute Heart Failure: Results of the MEDIT-AHF Study. JACC Heart Fail. 2018;6:52-62. doi: 10.1016/j.jchf.2017.09.020. PubMed PMID: 29226819.
  11. Tuttolomondo A, Di Raimondo D, Casuccio A, Velardo M, Salamone G, Cataldi M, et al. Mediterranean diet adherence and congestive heart failure: Relationship with clinical severity and ischemic pathogenesis. Nutrition. 2020;70:110584. doi: 10.1016/j.nut.2019.110584. PubMed PMID: 31759318.
  12. Tektonidis TG, Åkesson A, Gigante B, Wolk A, Larsson SC. Adherence to a Mediterranean diet is associated with reduced risk of heart failure in men. Eur J Heart Fail. 2016;18:253-9. doi: 10.1002/ejhf.481. PubMed PMID: 26781788.
  13. Bagheri M, Nouri M, Homayounfar R, Akhlaghi M. Association between adherence to the Mediterranean diet with cardiometabolic risk factors: a cross-sectional study on PERSIAN cohort study in Fasa. Sci Rep. 2023;13:14870. doi: 10.1038/s41598-023-41935-3. PubMed PMID: 37684269; PubMed Central PMCID: PMC10491824.
  14. Hu EA, Toledo E, Diez-Espino J, Estruch R, Corella D, Salas-Salvado J, et al. Lifestyles and risk factors associated with adherence to the Mediterranean diet: a baseline assessment of the PREDIMED trial. PLoS One. 2013;8:e60166. doi: 10.1371/journal.pone.0060166. PubMed PMID: 23637743; PubMed Central PMCID: PMC3639284.
  15. LaMonte MJ, Eaton CB. Physical Activity in the Treatment and Prevention of Heart Failure: An Update. Curr Sports Med Rep. 2021;20:410-7. doi: 10.1249/jsr.0000000000000869. PubMed PMID: 34357887; PubMed Central PMCID: PMC8351911.
  16. Opasich C, Meyers J. Working Group Report. European Heart Journal. 2001;22:125-35.
  17. Zores F, Iliou MC, Gellen B, Kubas S, Berthelot E, Guillo P, et al. Physical activity for patients with heart failure: Position paper from the heart failure (GICC) and cardiac rehabilitation (GERS-P) Working Groups of the French Society of Cardiology. Arch Cardiovasc Dis. 2019;112:723-31. doi: 10.1016/j.acvd.2019.07.003. PubMed PMID: 31542331.
  18. Pandey A, Patel KV, Vaduganathan M, Sarma S, Haykowsky MJ, Berry JD, et al. Physical Activity, Fitness, and Obesity in Heart Failure With Preserved Ejection Fraction. JACC Heart Fail. 2018;6:975-82. doi: 10.1016/j.jchf.2018.09.006. PubMed PMID: 30497652.
  19. Klompstra L, Jaarsma T, Strömberg A. Physical activity in patients with heart failure: barriers and motivations with special focus on sex differences. Patient Prefer Adherence. 2015;9:1603-10. doi: 10.2147/ppa.s90942. PubMed PMID: 26635469; PubMed Central PMCID: PMC4646589.
  20. World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects. Jama. 2013;310:2191-4. doi: 10.1001/jama.2013.281053. PubMed PMID: 24141714.
  21. Negarandeh R, Mahmoodi H, Noktehdan H, Heshmat R, Shakibazadeh E. Teach back and pictorial image educational strategies on knowledge about diabetes and medication/dietary adherence among low health literate patients with type 2 diabetes. Prim Care Diabetes. 2013;7:111-8. doi: 10.1016/j.pcd.2012.11.001. PubMed PMID: 23195913.
  22. Sikaroudi MK, Aghdam AK, Ebrahimi Z, Ramim T, Talebi A, Tabaeian SP, et al. Reliability and validity of the 14-item Mediterranean diet adherence screener among the healthy Iranian population. Govaresh. 2022;27:39-44. Persian.
  23. Bakhtari Aghdam F, Baghiani Moghaddam MH, Asghari Jafarabadi M, Allahverdipour H, Dabagh Nikookheslat S, Noorizadeh R. Explaining the role of personal, social and physical environment factors on employed women’s physical activity: a structural equation analysis. Glob J Health Sci. 2013;5:189-99. doi: 10.5539/gjhs.v5n4p189. PubMed PMID: 23777735; PubMed Central PMCID: PMC4776862.
  24. Vasheghani-Farahani A, Tahmasbi M, Asheri H, Ashraf H, Nedjat S, Kordi R. The Persian, last 7-day, long form of the International Physical Activity Questionnaire: translation and validation study. Asian J Sports Med. 2011;2:106-16. doi: 10.5812/asjsm.34781. PubMed PMID: 22375226; PubMed Central PMCID: PMC3289200.
  25. Masnoon N, Shakib S, Kalisch-Ellett L, Caughey GE. What is polypharmacy? A systematic review of definitions. BMC Geriatr. 2017;17:230. doi: 10.1186/s12877-017-0621-2. PubMed PMID: 29017448; PubMed Central PMCID: PMC5635569.
  26. Wu JR, Moser DK, Lennie TA, Burkhart PV. Medication adherence in patients who have heart failure: a review of the literature. Nurs Clin North Am. 2008;43:133-53. doi: 10.1016/j.cnur.2007.10.006. PubMed PMID: 18249229.
  27. Larina V, Zamyatin K, Gudiev CG. Medication adherence in patients with heart failure: a pilot observational study in outpatient practice. Russian Journal of Cardiology. 2024;29:6180. doi: 10.15829/1560-4071-2024-6180.
  28. Forsyth P, Richardson J, Lowrie R. Patient-reported barriers to medication adherence in heart failure in Scotland. Int J Pharm Pract. 2019;27:443-50. doi: 10.1111/ijpp.12511. PubMed PMID: 30675955.
  29. Bayerle P, Beyer S, Tegtbur U, Kück M, Adel J, Kwast S, et al. Exercise Capacity, Iron Status, Body Composition, and Mediterranean Diet in Patients with Chronic Heart Failure. Nutrients. 2022;15. doi: 10.3390/nu15010036. PubMed PMID: 36615693; PubMed Central PMCID: PMC9824214.
  30. Dos Reis Padilha G, Sanches Machado d’Almeida K, Ronchi Spillere S, Corrêa Souza G. Dietary Patterns in Secondary Prevention of Heart Failure: A Systematic Review. Nutrients. 2018;10. doi: 10.3390/nu10070828. PubMed PMID: 29949894; PubMed Central PMCID: PMC6073256.
  31. Tektonidis TG, Åkesson A, Gigante B, Wolk A, Larsson SC. A Mediterranean diet and risk of myocardial infarction, heart failure and stroke: A population-based cohort study. Atherosclerosis. 2015;243:93-8. doi: 10.1016/j.atherosclerosis.2015.08.039. PubMed PMID: 26363438.
  32. Ponikowski P, Voors AA, Anker SD, Bueno H, Cleland JG, Coats AJ, et al. 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Kardiol Pol. 2016;74:1037-147. doi: 10.5603/kp.2016.0141. PubMed PMID: 27748494.
  33. Jordan C, Charman SJ, Batterham AM, Flynn D, Houghton D, Errington L, et al. Habitual physical activity levels of adults with heart failure: systematic review and meta-analysis. Heart. 2023;109:1357-62. doi: 10.1136/heartjnl-2022-321943. PubMed PMID: 36849238; PubMed Central PMCID: PMC10511969.
  34. Cattadori G, Segurini C, Picozzi A, Padeletti L, Anzà C. Exercise and heart failure: an update. ESC Heart Fail. 2018;5:222-32. doi: 10.1002/ehf2.12225. PubMed PMID: 29235244; PubMed Central PMCID: PMC5880674.
  35. Heidenreich PA, Bozkurt B, Aguilar D, Allen LA, Byun JJ, Colvin MM, et al. 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation. 2022;145:e895-e1032. doi: 10.1161/cir.0000000000001063. PubMed PMID: 35363499.
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