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طیبی, مریم, پورخسرو, آذر, متوسل, مریم. (1404). فناوری نانو در تشخیص، درمان و پیشگیری از عفونت‌های ویروسی. سامانه مدیریت نشریات علمی, 14(1), 237-250. doi: 10.30476/smsj.2026.106607.1629
مریم طیبی; آذر پورخسرو; مریم متوسل. "فناوری نانو در تشخیص، درمان و پیشگیری از عفونت‌های ویروسی". سامانه مدیریت نشریات علمی, 14, 1, 1404, 237-250. doi: 10.30476/smsj.2026.106607.1629
طیبی, مریم, پورخسرو, آذر, متوسل, مریم. (1404). 'فناوری نانو در تشخیص، درمان و پیشگیری از عفونت‌های ویروسی', سامانه مدیریت نشریات علمی, 14(1), pp. 237-250. doi: 10.30476/smsj.2026.106607.1629
طیبی, مریم, پورخسرو, آذر, متوسل, مریم. فناوری نانو در تشخیص، درمان و پیشگیری از عفونت‌های ویروسی. سامانه مدیریت نشریات علمی, 1404; 14(1): 237-250. doi: 10.30476/smsj.2026.106607.1629

فناوری نانو در تشخیص، درمان و پیشگیری از عفونت‌های ویروسی

مجله علوم پزشکی صدرا
مقاله 20، دوره 14، شماره 1، فروردین 1405، صفحه 237-250    اصل مقاله (573.72 K)
نوع مقاله: مقاله مروری
شناسه دیجیتال (DOI): 10.30476/smsj.2026.106607.1629
نویسندگان
مریم طیبی1، 2؛ آذر پورخسرو3؛ مریم متوسل* 2
1کمیته تحقیقات دانشجویی، دانشگاه علوم پزشکی شیراز
2گروه علوم آزمایشگاهی، دانشکده پیراپزشکی، دانشگاه علوم پزشکی شیراز
3گروه فارماکولوژی، دانشکده پزشکی، دانشگاه علوم پزشکی شیراز
چکیده
داروهای ضد ویروس فعلی با مشکلات متعددی مانند نیمه‌عمر کوتاه، حلالیت ضعیف در آب، عملکرد غیراختصاصی و عوارض جانبی فراوان همراه هستند. علاوه بر این، ظهور پدیده مقاومت دارویی و عدم پاسخ‌دهی کافی ویروس‌ها به داروهای ضد ویروس نیز از جمله مسائلی است که درمان عفونت‌های ویروسی را با چالش‌های زیادی روبه‌رو کرده است. مجموعه این عوامل سبب افزایش نیاز به استراتژی‌های نوین درمانی گردیده است. در این زمینه، فناوری نانو می‌تواند به‌عنوان یک راه حل نویدبخش مطرح شود. مطالعه مروری حاضر، بر اساس بررسی مقالات مرتبط با کاربرد فناوری نانو در پیشگیری، تشخیص و درمان بیماری‌های ویروسی که در فاصله بین سال‌های 2009 تا 2023 میلادی در مجلات علمی معتبر منتشر و در پایگاه‌های استنادی پابمد، گوگل اسکالر و وب آو ساینس نمایه شده‌اند، تدوین شده است. پژوهش‌های اخیر نشان داده‌اند که نانوحامل‌های دارویی، انتقال دارو به هدف مورد نظر را آسان نموده‌اند. نانو ذراتی مانند ذرات کوانتومی طلا، روی، پلاتین و پالادیوم باعث افزایش حساسیت و سرعت تشخیص ویروس‌ها شده‌اند. همچنین استفاده از نانو حامل‌های دارویی سبب رفع محدودیت‌های فیزیکوشیمیایی داروهای ضد ویروس، کاهش میزان سمیت و عوارض جانبی، افزایش عملکرد انتخابی (عدم تأثیر بر سلول‌های انسانی) و بهبود اثربخشی و فعالیت ضد ویروسی آن‌ها گردیده است. 

تازه های تحقیق

Maryam Tayebi (Google Scholar)

Maryam Motevasel (Google Scholar)

کلیدواژه‌ها
فناوری نانو؛ بیماری‌های ویروسی؛ داروهای ضد ویروس؛ تشخیص ویروس‌ها؛ واکسن‌های ویروسی؛ پیشگیری و کنترل
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