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Aleebrahim, Forugh, Mahboobi, Marzieh, Rezaee, Fatemeh, Nasirian, Maryam. (1404). Research Priorities for Human Immunodeficiency Virus and Acquired Immune Deficiency Syndrome in Iran: A Mixed-Methods Study Combining a Systematic Review and Delphi Consensus Approach. سامانه مدیریت نشریات علمی, (), -. doi: 10.30476/ijms.2025.104577.3819
Forugh Aleebrahim; Marzieh Mahboobi; Fatemeh Rezaee; Maryam Nasirian. "Research Priorities for Human Immunodeficiency Virus and Acquired Immune Deficiency Syndrome in Iran: A Mixed-Methods Study Combining a Systematic Review and Delphi Consensus Approach". سامانه مدیریت نشریات علمی, , , 1404, -. doi: 10.30476/ijms.2025.104577.3819
Aleebrahim, Forugh, Mahboobi, Marzieh, Rezaee, Fatemeh, Nasirian, Maryam. (1404). 'Research Priorities for Human Immunodeficiency Virus and Acquired Immune Deficiency Syndrome in Iran: A Mixed-Methods Study Combining a Systematic Review and Delphi Consensus Approach', سامانه مدیریت نشریات علمی, (), pp. -. doi: 10.30476/ijms.2025.104577.3819
Aleebrahim, Forugh, Mahboobi, Marzieh, Rezaee, Fatemeh, Nasirian, Maryam. Research Priorities for Human Immunodeficiency Virus and Acquired Immune Deficiency Syndrome in Iran: A Mixed-Methods Study Combining a Systematic Review and Delphi Consensus Approach. سامانه مدیریت نشریات علمی, 1404; (): -. doi: 10.30476/ijms.2025.104577.3819

Research Priorities for Human Immunodeficiency Virus and Acquired Immune Deficiency Syndrome in Iran: A Mixed-Methods Study Combining a Systematic Review and Delphi Consensus Approach

Iranian Journal of Medical Sciences
مقالات آماده انتشار، اصلاح شده برای چاپ، انتشار آنلاین از تاریخ 24 آذر 1404    اصل مقاله (1.85 M)
نوع مقاله: Original Article(s)
شناسه دیجیتال (DOI): 10.30476/ijms.2025.104577.3819
نویسندگان
Forugh Aleebrahim1؛ Marzieh Mahboobi2؛ Fatemeh Rezaee3؛ Maryam Nasirian* 4، 5
1Department of Public Health, Torbat-Jam Faculty of Medical Sciences, Torbat-Jam, Iran
2HIV/AIDS Control Office, Center for Communicable Diseases, Ministry of Health, Tehran, Iran
3Student Research Committee, Faculty of Health, Isfahan University of Medical Sciences, Isfahan, Iran
4Department of Epidemiology and Biostatistics, Faculty of Health, Isfahan University of Medical Science, Isfahan, Iran
5Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
چکیده
Background: In 2022, human immunodeficiency virus (HIV) affected 39 million globally, with Iran experiencing a concentrated epidemic. This study aimed to identify and prioritize critical HIV/AIDS research areas to address existing gaps in the Iranian context.
Methods: Researchers at Isfahan University of Medical Sciences employed a three-phase approach between May 2018 and March 2023. The first phase involved developing an HIV research matrix tailored to international guidelines and the Iranian context. In the second phase, a systematic review of HIV-related studies in Iran was conducted following the PRISMA protocol to assess quality and relevance. The third phase utilized a three-round Delphi method to collect expert feedback, which was used to prioritize research areas based on their importance and feasibility.
Results: A systematic review of 6,310 sources yielded 745 documents for full-text analysis. Key research domains identified included prevention, diagnosis, care and treatment, epidemiology, and co-infections. Quantitative analysis indicated that 23% of studies focused on co-infections, while ethical issues were addressed in only 0.04%. Qualitative assessment revealed that 54% of reviewed studies were of low quality. Subsequent expert consultation and multi-criteria decision analysis ranked laboratory research and co-infections as the highest priorities. Specific sub-areas identified included molecular epidemiology and interventions addressing stigma and discrimination. Despite being highly cost-effective and urgently needed, research on stigma-related interventions exhibited a significant gap.
Conclusion: The study identified 11 main research areas and 60 sub-areas as priorities for HIV/AIDS research in Iran, highlighting the need for strategic funding and research planning. Ethical considerations and laboratory improvements are essential for enhancing public health outcomes and addressing emerging challenges in the HIV epidemic.

تازه های تحقیق

Forugh Aleebrahim (Google Scholar) 
Maryam Nasirian (Google Scholar)

کلیدواژه‌ها
HIV؛ Acquired immune deficiency syndrome؛ Health priorities؛ Research؛ Iran
مراجع
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