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Exploring Non-Genetic Factors in Cancer Resistance among Ramsar Residents: From Medical Geology to the Role of Diet: A Review | ||
| International Journal of Nutrition Sciences | ||
| مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 09 آذر 1404 اصل مقاله (329.78 K) | ||
| نوع مقاله: Review Article | ||
| شناسه دیجیتال (DOI): 10.30476/ijns.2025.105774.1404 | ||
| نویسندگان | ||
| Hassan Bahrami1؛ Pouya Zohdparast2؛ Hassan Vafapour3؛ AmirAli Fallah4؛ Seyed Mohammad Javad Mortazavi* 3، 4؛ Fateme Zaker3؛ Maryam Arshadi3؛ Alireza Mortazavi5؛ Seyed Jalil Masoumi* 6، 7، 8 | ||
| 1Independent Health/Nutrition Researcher, Tehran, Iran | ||
| 2Petroleum Engineering, Institute of Petroleum Engineering, University of Tehran, Tehran, Iran | ||
| 3Ionizing and Non-Ionizing Radiation Protection Research Center, Shiraz University of Medical Sciences, Shiraz, Iran | ||
| 4Department of Medical Physics and Engineering, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran | ||
| 5Caldecot Centre, King's College Hospital NHS Foundation Trust, London, UK | ||
| 6Nutrition Research Center, Shiraz University of Medical Science, Shiraz, Iran | ||
| 7Department of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Science, Shiraz, Iran | ||
| 8Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran | ||
| چکیده | ||
| Ramsar in northern Iran provides a unique natural setting to investigate the biological effects of exposure to chronic radiation and the potential adaptive mechanisms. It is owing to its exceptional high concentrations of radium in sedimentary rocks, hot springs, and the elevated indoor radon levels. Despite prolonged exposure, available evidences did not demonstrate an increased incidence of cancer among local residents, which may indicate adaptive biological responses or protective lifestyle factors, although a causal relationship has not been established. Beyond potential genetic influences, it can be hypothesized that the predominantly vegetarian diet of Ramsar inhabitants, rich in raw vegetables, fruits, nuts, and garlic, may contribute to the reduced cancer risk through its antioxidant and anti-inflammatory effects. To explore the relatively low cancer incidence observed in this population, this review assessed existing evidences in relation to the potential protective role of diet against cancer and compared these findings with populations consuming acidogenic diets high in processed foods and animal proteins. The evidences collectively suggested that lifestyle and dietary factors may influence the biological impact of environmental stressors such as chronic exposure to natural radiations. | ||
| کلیدواژهها | ||
| Cancer resistance؛ Geology؛ Non-genetic factors؛ Diet؛ Iran | ||
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آمار تعداد مشاهده مقاله: 16 تعداد دریافت فایل اصل مقاله: 35 |
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