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The FODMAP diet for Gut Microbiome Restoration in Patients with Irritable Bowel Syndrome: A Narrative Review | ||
| Iranian Journal of Colorectal Research | ||
| مقاله 4، دوره 13، شماره 2، شهریور 2025 اصل مقاله (1.42 M) | ||
| نوع مقاله: Narrative Review | ||
| شناسه دیجیتال (DOI): 10.30476/acrr.2025.108357.1256 | ||
| نویسندگان | ||
| Reimara Valk* 1؛ Mieke Jozina Valk2 | ||
| 1Department of Management, School of Business, American University in Dubai, Dubai, UAE | ||
| 2General Medical Practice, Kamperland, Zeeland, The Netherlands | ||
| چکیده | ||
| Irritable Bowel Syndrome (IBS) is a multifactorial, debilitating, complex, and chronic disorder of gut-brain interaction. The Gut microbiota and its metabolites play an important role in the etiology, pathogenesis, and pathophysiology of IBS. Dietary modulation of the gut microbiome to correct gut microbiota dysbiosis and restore host-microbe eubiosis is considered an effective strategy for managing IBS. Increasing evidence suggests that a diet low in fermentable oligo-, di-, and monosaccharides, and polyols (FODMAPs) can beneficially modulate the gut microbiota. The objective of this narrative review is to elucidate how a FODMAP diet impacts the gut microbiome. Understanding how this diet influences gut microbial communities is crucial for understanding the potential long-term health consequences of this dietary regimen. This nuanced understanding can inform the development of optimal, personalized FODMAP dietary strategies tailored to the individual gut microbiome composition and function of IBS patients. A search was conducted in the electronic databases PubMed/Medline, SCOPUS, and Web of Science for observational studies, clinical trials, systematic reviews, and meta-analyses published between 2012 and 2025. Search terms and keywords included IBS, FODMAP diet, gut microbiome, and gut microbiota. Contrary to the prevailing belief that a diet low in FODMAPs has detrimental effects on gut health, scientific studies show that such a diet can have beneficial effects on both gut and host health. The scientific evidence presented in this narrative review supports the FODMAP diet as a personalized precision nutrition therapy that can effectively restore, reinoculate, and rebalance the gut microbiome. | ||
| کلیدواژهها | ||
| Irritable Bowel Syndrome؛ Gut microbiota؛ FODMAP-diet؛ IBS-symptoms personalized precision-nutrition | ||
| مراجع | ||
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