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Doustaki Zaboli, Maryam, Joukar, Siyavash, Nouzari, Masoumeh, Aminizadeh, Soheil, Kahnooji, Masoomeh, Mohammadi, Khadijeh. (1404). Heart Rate Variability and Blood Pressure Response to Low-Intensity Endurance Exercise Training Plus Blood Flow Restriction in Individuals with Mild Hypertension: A Randomized Controlled Clinical Trial. سامانه مدیریت نشریات علمی, (), -. doi: 10.30476/ijms.2025.105405.3916
Maryam Doustaki Zaboli; Siyavash Joukar; Masoumeh Nouzari; Soheil Aminizadeh; Masoomeh Kahnooji; Khadijeh Mohammadi. "Heart Rate Variability and Blood Pressure Response to Low-Intensity Endurance Exercise Training Plus Blood Flow Restriction in Individuals with Mild Hypertension: A Randomized Controlled Clinical Trial". سامانه مدیریت نشریات علمی, , , 1404, -. doi: 10.30476/ijms.2025.105405.3916
Doustaki Zaboli, Maryam, Joukar, Siyavash, Nouzari, Masoumeh, Aminizadeh, Soheil, Kahnooji, Masoomeh, Mohammadi, Khadijeh. (1404). 'Heart Rate Variability and Blood Pressure Response to Low-Intensity Endurance Exercise Training Plus Blood Flow Restriction in Individuals with Mild Hypertension: A Randomized Controlled Clinical Trial', سامانه مدیریت نشریات علمی, (), pp. -. doi: 10.30476/ijms.2025.105405.3916
Doustaki Zaboli, Maryam, Joukar, Siyavash, Nouzari, Masoumeh, Aminizadeh, Soheil, Kahnooji, Masoomeh, Mohammadi, Khadijeh. Heart Rate Variability and Blood Pressure Response to Low-Intensity Endurance Exercise Training Plus Blood Flow Restriction in Individuals with Mild Hypertension: A Randomized Controlled Clinical Trial. سامانه مدیریت نشریات علمی, 1404; (): -. doi: 10.30476/ijms.2025.105405.3916

Heart Rate Variability and Blood Pressure Response to Low-Intensity Endurance Exercise Training Plus Blood Flow Restriction in Individuals with Mild Hypertension: A Randomized Controlled Clinical Trial

Iranian Journal of Medical Sciences
مقالات آماده انتشار، اصلاح شده برای چاپ، انتشار آنلاین از تاریخ 28 مهر 1404    اصل مقاله (4.38 M)
نوع مقاله: Original Article(s)
شناسه دیجیتال (DOI): 10.30476/ijms.2025.105405.3916
نویسندگان
Maryam Doustaki Zaboli1؛ Siyavash Joukar* 2، 3؛ Masoumeh Nouzari4؛ Soheil Aminizadeh1، 3؛ Masoomeh Kahnooji2، 5؛ Khadijeh Mohammadi1
1Physiology Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran
2Cardiovascular Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Sciences, Kerman, Iran
3Department of Physiology and Pharmacology, Afzalipour Medical Faculty, Kerman University of Medical Sciences, Kerman, Iran
4Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran
5Department of Cardiology, Afzalipour Medical Faculty, Kerman University of Medical Sciences, Kerman, Iran
چکیده
Background: Given limited available data and information gaps related to the effects of endurance exercise along with blood flow restriction (BFR) on the heart. This study examined the effects of low-intensity endurance exercise training (Ex) alone and BFR on blood pressure (BP), electrocardiogram (ECG), heart rate variability (HRV), and heart rate recovery time (HRRT) in participants with grade 1 hypertension.
Methods: In this randomized double-blind clinical trial, 43 hypertensive participants, 50-65 years old, were randomly divided into three groups: Ex+BFR, Ex, and the control (Con) group. The training program was conducted three times weekly for 10 weeks in spring 2024 at Kerman University of Medical Sciences. Before and 24 hours after the intervention, HRV parameters, BP, ECG, and HRRT were assessed.
Results: The Ex and Ex+BFR groups showed a significant increase in Root Mean Square of Successive Differences between normal heartbeats (RMSSD) (P=0.008, P=0.002), Standard Deviation of Successive Differences (SDSD) (P=0.008, P=0.002),  and the standard deviation of the Poincaré plot ratio (SD1/SD2) (P=0.0004, P=0.0002), and a reduced low frequency to high frequency ratio (LF/HF) (P=0.013 and P=0.007) compared to Con group, respectively. The Ex+BFR group demonstrated a greater positive effect on frequency-domain parameters of HRV. In addition, both the Ex and Ex+BFR groups showed a significant reduction in HRRT (P=0.0001 vs. relevant baseline), mean arterial blood pressure (MAP) (P=0.0001), and prolonged PR interval (P=0.038 and P=0.035, respectively) and shortened QRS complex compared to the Con group.
Conclusion: This study demonstrates that combining low-intensity endurance exercise with BFR exerts a positive effect on cardiovascular parameters such as BP, ECG, HRRT, and demonstrates superior effects on HRV compared to exercise alone in individuals with mild hypertension.

تازه های تحقیق

Maryam Doustaki Zaboli (Google Scholar)

Siyavash Joukar (Google Scholar)

کلیدواژه‌ها
Heart rate؛ Endurance training؛ Blood flow restriction؛ Blood pressure
مراجع
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