1Supporting the Family and the Youth of Population Research Core, Department of Obstetrics and Gynecology, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran
2Department of Pediatric Surgery, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
چکیده
Oropharyngeal teratoma (OPT) is a rare congenital tumor that may present either in isolation or in conjunction with craniofacial anomalies, often posing a major risk to infant survival. Recent advances in prenatal imaging, particularly high-resolution ultrasonography, have significantly improved the early detection and characterization of such tumors, enhancing clinical decision-making. Although prenatal sonography and MRI typically enable early diagnosis, the present study reported a case of OPT, diagnosed postpartum in an Iranian female infant weighing 4300 g. Despite the absence of prenatal diagnosis, the mass was successfully managed through prompt surgical intervention. The outcome was favorable, with no complications or recurrence. This case highlighted the critical role of early diagnosis and multidisciplinary perinatal planning in improving the prognosis of rare congenital tumors such as OPT.
Nguyen PTA, Lavisha P, Lynn KH, Jitendrakumar VS. Case report: Congenital palatal teratoma (epignathus) leading to neonatal airway obstruction. Int J Surg Case Rep. 2023;109:108518. doi: 10.1016/j.ijscr.2023.108518. PubMed PMID: 37517249; PubMed Central PMCID: PMCPMC10407423.
Zhu P, Li XY. Management of oropharyngeal teratoma: Two case reports and a literature review. J Int Med Res. 2021;49:300060521996873. doi: 10.1177/0300060521996873. PubMed PMID: 33641494; PubMed Central PMCID: PMCPMC7917885.
Narayan R, Ahmad MS, Sr., Kumar A. Fetal Oropharyngeal Teratoma: Prenatal Diagnosis and Imaging Characteristics. Cureus. 2020;12:e11329. doi: 10.7759/cureus.11329. PubMed PMID: 33304667; PubMed Central PMCID: PMCPMC7719477.
Milani HJ, Araujo Junior E, Cavalheiro S, Oliveira PS, Hisaba WJ, Barreto EQ, et al. Fetal brain tumors: Prenatal diagnosis by ultrasound and magnetic resonance imaging. World J Radiol. 2015;7:17-21. doi: 10.4329/wjr.v7.i1.17. PubMed PMID: 25628801; PubMed Central PMCID: PMCPMC4295174.
Garcia-Diaz L, Chimenea A, de Agustin JC, Pavon A, Antinolo G. Ex-Utero Intrapartum Treatment (EXIT): indications and outcome in fetal cervical and oropharyngeal masses. BMC Pregnancy Childbirth. 2020;20:598. doi: 10.1186/s12884-020-03304-0. PubMed PMID: 33028259; PubMed Central PMCID: PMCPMC7541246.
Gonzalez-Cantu CM, Moreno-Pena PJ, Salazar-Lara MG, Garcia PPF, Montes-Tapia FF, Cervantes-Kardasch VH, et al. Surgical management of palatal teratoma (epignathus) with the use of virtual reconstruction and 3D models: a case report and literature review. Arch Plast Surg. 2021;48:518-23. doi: 10.5999/aps.2021.00318. PubMed PMID: 34583437; PubMed Central PMCID: PMCPMC8490109.
Glowska-Ciemny J, Szymanski M, Kuszerska A, Rzepka R, von Kaisenberg CS, Kocylowski R. Role of Alpha-Fetoprotein (AFP) in Diagnosing Childhood Cancers and Genetic-Related Chronic Diseases. Cancers (Basel). 2023;15. doi: 10.3390/cancers15174302. PubMed PMID: 37686577; PubMed Central PMCID: PMCPMC10486785.
Glowska-Ciemny J, Szmyt K, Kuszerska A, Rzepka R, von Kaisenberg C, Kocylowski R. Fetal and Placental Causes of Elevated Serum Alpha-Fetoprotein Levels in Pregnant Women. J Clin Med. 2024;13. doi: 10.3390/jcm13020466. PubMed PMID: 38256600; PubMed Central PMCID: PMCPMC10816536.
