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The Effect of Fermented Green Fern Extract (S. palustris) on Tumor Necrosis Factor-Alpha and Superoxide Dismutase Levels in Malnourished Rats | ||
| International Journal of Nutrition Sciences | ||
| مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 23 شهریور 1404 اصل مقاله (1.15 M) | ||
| نوع مقاله: Original Article | ||
| شناسه دیجیتال (DOI): 10.30476/ijns.2025.105137.1384 | ||
| نویسندگان | ||
| Jurianto Gambir؛ Tonny Cortis Maigoda* ؛ Meriwati Mahyuddin؛ Ikawati Sulistyaningsih | ||
| Department of Nutrition, Poltekkes Kemenkes Pontianak, Pontianak, Indonesia | ||
| چکیده | ||
| Background: Malnutrition in children is still a global issue that can significantly impact the immune function and increase the susceptibility to oxidative stress. This study investigated the potential of fermented S. palustris on oxidative stress markers, specifically Superoxide Dismutase (SOD) and Tumor Necrosis Factor-alpha (TNF-α), in malnourished rats. Methods: The rats were divided into five groups of healthy controls, malnourished without intervention, and malnourished groups receiving varying doses of S. palustris extract (100, 300, and 500 mg/kg) for 28 days. Results: A significant increase in SOD level in all intervention groups was noticed with the highest increase in 500 mg/kg group (D3) that approached the level of the healthy control group. TNF-α level significantly decreased in the intervention groups, with the 300 mg/kg (D2) group showing the greatest reduction. Conclusion: Fermented S. palustris extract was shown to enhance antioxidant properties and reduce inflammation in malnourished animals that can offer a promising strategy for nutritional interventions in malnutrition-related disorders. | ||
تازه های تحقیق | ||
Jurianto Gambir (Google Scholar)
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| کلیدواژه‌ها | ||
| Malnutrition؛ Stenochlaena palustris؛ Fermentation؛ Superoxide Dismutase؛ Tumor Necrosis Factor-alpha | ||
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آمار تعداد مشاهده مقاله: 3 تعداد دریافت فایل اصل مقاله: 2 |
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