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The Effects of Diet and Cryolipolysis on Anxiety and Depression in Subjects with Overweight: A Randomize controlled Clinical Trial | ||
| International Journal of Nutrition Sciences | ||
| مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 28 تیر 1404 اصل مقاله (746.19 K) | ||
| نوع مقاله: Original Article | ||
| شناسه دیجیتال (DOI): 10.30476/ijns.2025.104928.1374 | ||
| نویسندگان | ||
| Hossein Hatamzadeh1؛ Mohsen Vasegh Abbasi2؛ Seyede-vida Hosseini3؛ Mahmoud Ebrahimi4؛ Mina Nosrati3؛ Habibollah Esmaily5، 6؛ Maryam Alinezhad-Namaghi1؛ Maryam Mohammadi Bajgiran7؛ Gordon A.Ferns8؛ Sara Ghazi Zadeh9؛ Maryam Saberi-Karimian* 7؛ Majid Ghayour-Mobarhan* 10؛ Reza Assaran-Darban11 | ||
| 1Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Science, Mashhad, Iran | ||
| 2Department of Biology, Mashhad Branch, Islamic Azad University, Mashhad, Iran | ||
| 3Department of Nutrition Sciences, Varastegan Institude for Medical Sciences, Mashhad Iran | ||
| 4Cardiovascular Research Center, Mashhad University of Medical Sciences, Mashhad, Iran | ||
| 5Social Determinants of Health Research Center, Mashhad University of Medical Sciences, Mashhad, Iran | ||
| 6Department of Biostatistics, School of Health, Mashhad University of Medical Sciences, Mashhad Iran | ||
| 7Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran | ||
| 8Brighton and Sussex Medical School, Division of Medical Education, Falmer, Brighton, Sussex BN1 9PH, UK | ||
| 9International UNESCO center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran | ||
| 10International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran | ||
| 11Department of Biology, Mashhad Branch, Islamic Azad University, Mashhad, Iran. | ||
| چکیده | ||
| Background: Obesity has been managed using different treatments including cryolipolysis; while a relationship was reported between obesity and mental disorders too. This study aimed to assess the effect of low caloric diet plus cryolipolysis on depression and anxiety in comparison to low caloric diet alone in overweight subjects. Methods: In a randomized controlled clinical trial, 50 healthy overweight females (25 kg/m2≤ body mass index (BMI)<30 kg/m2) aged 18 to 65 years were recruited in this study. Subjects were randomly allocated to two groups who received a calorie restricted diet with and without cryolipolysis. Anthropometrics and serum biochemistry tests were undertaken to measure the baseline and the end of the study (8th week). Depression and anxiety were assessed using the body shape questionnaire (BSQ), Beck’s depression inventory (BDI) and Beck Anxiety Index (BAI) tests at the beginning and the end of study. Results: All participants completed the study period. A significant difference was found in the BSQ at the baseline and the end of study between the intervention and control groups (9.96±18.61 vs. -19.24±26.55, respectively, p<0.001). A significant difference was found in BAI (-3.52±7.63 vs. 1.08±7.01, respectively, p=0.031) between the two groups. BDI changes between the two groups did not differ significantly (p>0.05). Conclusion: Cryolipolysis was demonstrated to improve the anxiety in overweight subjects. The molecular mechanism is not clear yet and further studies with a large sample size are necessary to be investigated. | ||
| کلیدواژه‌ها | ||
| Cryolipolysis؛ Diet؛ Depression؛ Anxiety؛ Iran | ||
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