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Omega 3-Induced Autophagy: A Two-Sided Sword in Cell Death from Historical Perspective in Clinical Application and Biological Mechanisms | ||
| International Journal of Nutrition Sciences | ||
| مقاله 3، دوره 10، شماره 3، آذر 2025، صفحه 395-405 اصل مقاله (714.9 K) | ||
| نوع مقاله: Review Article | ||
| شناسه دیجیتال (DOI): 10.30476/ijns.2025.104987.1379 | ||
| نویسندگان | ||
| Razieh Tabaeifard1؛ Marzieh Zare1؛ Abolfazl Zendehdel2؛ Soraiya Ebrahimpour-Koujan* 3، 4 | ||
| 1Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran | ||
| 2Geriatric Department, Ziayian Hospital, Tehran University of Medical Sciences, Tehran, Iran | ||
| 3Department of Clinical Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran | ||
| 4Cancer Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, Tehran, Iran | ||
| چکیده | ||
| Omega-3 fatty acids, including eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and α-linolenic acid (ALA), are polyunsaturated fatty acids (PUFAs) with numerous health benefits. They play a critical role in various cellular functions, such as maintaining cell membrane integrity, cellular signaling pathways, and cell-to-cell communication. Omega-3s are known for their anti-inflammatory, anti-cancer, anti-depressant, and lipid-lowering properties. Autophagy, a cellular process responsible for recycling and degrading cellular components, is closely linked to these fatty acids. The impact of omega-3 fatty acids on autophagy signaling pathways hold promise for innovative therapeutic strategies in disease management and overall well-being. This review explores the influence of omega-3 fatty acids on autophagy and provides insights into the potential mechanisms involved. | ||
تازه های تحقیق | ||
Razieh Tabaeifard (Google Scholar) Soraiya Ebrahimpour-Koujan (Google Scholar) | ||
| کلیدواژهها | ||
| Cellular autophagy؛ Omega-3؛ Cell death؛ Docosahexaenoic acid؛ Eicosapentaenoic acid | ||
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آمار تعداد مشاهده مقاله: 313 تعداد دریافت فایل اصل مقاله: 400 |
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