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Ostovar, Mohadeseh, Hosseinzadeh, Ahmad, Heydari, Mojtaba, Moghadam, Mahsa, Shams, Mesbah. (1404). Septic Gangrene and Thrombophlebitis Following Leech Therapy in a Patient with Undiagnosed Arterial Occlusive Disease: A Case Report. سامانه مدیریت نشریات علمی, 50(8), 581-585. doi: 10.30476/ijms.2025.105450.3922
Mohadeseh Ostovar; Ahmad Hosseinzadeh; Mojtaba Heydari; Mahsa Moghadam; Mesbah Shams. "Septic Gangrene and Thrombophlebitis Following Leech Therapy in a Patient with Undiagnosed Arterial Occlusive Disease: A Case Report". سامانه مدیریت نشریات علمی, 50, 8, 1404, 581-585. doi: 10.30476/ijms.2025.105450.3922
Ostovar, Mohadeseh, Hosseinzadeh, Ahmad, Heydari, Mojtaba, Moghadam, Mahsa, Shams, Mesbah. (1404). 'Septic Gangrene and Thrombophlebitis Following Leech Therapy in a Patient with Undiagnosed Arterial Occlusive Disease: A Case Report', سامانه مدیریت نشریات علمی, 50(8), pp. 581-585. doi: 10.30476/ijms.2025.105450.3922
Ostovar, Mohadeseh, Hosseinzadeh, Ahmad, Heydari, Mojtaba, Moghadam, Mahsa, Shams, Mesbah. Septic Gangrene and Thrombophlebitis Following Leech Therapy in a Patient with Undiagnosed Arterial Occlusive Disease: A Case Report. سامانه مدیریت نشریات علمی, 1404; 50(8): 581-585. doi: 10.30476/ijms.2025.105450.3922

Septic Gangrene and Thrombophlebitis Following Leech Therapy in a Patient with Undiagnosed Arterial Occlusive Disease: A Case Report

Iranian Journal of Medical Sciences
مقاله 8، دوره 50، شماره 8، آبان 2025، صفحه 581-585    اصل مقاله (1 M)
نوع مقاله: Case Report(s)
شناسه دیجیتال (DOI): 10.30476/ijms.2025.105450.3922
نویسندگان
Mohadeseh Ostovar1؛ Ahmad Hosseinzadeh2؛ Mojtaba Heydari3؛ Mahsa Moghadam4؛ Mesbah Shams* 5
1Research Center for Traditional Medicine and History of Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
2Department of Vascular Surgery, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
3Poostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
4Department of Internal Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
5Endocrinology and Metabolism Research Center, Shiraz University of Medical Sciences, Shiraz, Iran, Shiraz University of Medical Sciences, Shiraz, Iran
چکیده
Different side effects have been reported for leech therapy, such as local itching, skin reactions, infection, bleeding disorders, and anemia. The present study described a rare and lethal adverse event following leech therapy.
A 63-year-old man was referred to Nemazee Teaching Hospital (Shiraz, Iran) in December 2020 with a two-week history of progressive right lower extremity swelling, erythema, and ecchymosis. One week before symptom onset, he had undergone leech therapy on the lateral calf and upper thigh of the right lower extremity, administered by a traditional healer. Physical examination revealed gangrene of the right leg and absence of all pulses. Color Doppler sonography of the leg and computed tomography angiography (CTA) of the thoracic aorta to the lower extremities revealed complete thrombosis of all right lower extremity arteries, extending to the right iliac artery and abdominal aorta. With a diagnosis of arterial occlusive disease and septic thrombophlebitis, the patient received intravenous antibiotics and anticoagulant therapy. Due to the inadequacy of medical treatments, a right lower extremity amputation was performed. The patient expired 5 days postoperatively due to septic shock and multiorgan failure. 

تازه های تحقیق

Mohadeseh Ostovar (Google Scholar)

Mesbah Shams (Google Scholar)

کلیدواژه‌ها
Leeching؛ Thrombophlebitis؛ Infections؛ Long term adverse effects؛ Mortality
مراجع
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  10. Sepaskhah M, Yazdanpanah N, Sari Aslani F, Akbarzadeh Jahromi M. Cutaneous Pseudolymphoma As a Rare Adverse Effect of Medicinal Leech Therapy: A Case Report and Review of the Literature. Cureus. 2020;12:e7517. doi: 10.7759/cureus.7517. PubMed PMID: 32377465; PubMed Central PMCID: PMCPMC7198106.
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