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Sakaray, Yashwant, Maheshwari, Naveeen, Thakur, Manish, J, Sisira, Kurdia, Kailash, Irrinki, Santosh, Subbiah Nagaraj, Satish, Kaman, Lileswar. (1403). Presentation and Outcomes of Patients with Colorectal Malignancies Undergoing Emergency Surgery – Experience from a Tertiary Care Centre in India. سامانه مدیریت نشریات علمی, 13(1), 8-14. doi: 10.30476/acrr.2025.105365.1235
Yashwant Sakaray; Naveeen Maheshwari; Manish Thakur; Sisira J; Kailash Chand Kurdia; Santosh Irrinki; Satish Subbiah Nagaraj; Lileswar Kaman. "Presentation and Outcomes of Patients with Colorectal Malignancies Undergoing Emergency Surgery – Experience from a Tertiary Care Centre in India". سامانه مدیریت نشریات علمی, 13, 1, 1403, 8-14. doi: 10.30476/acrr.2025.105365.1235
Sakaray, Yashwant, Maheshwari, Naveeen, Thakur, Manish, J, Sisira, Kurdia, Kailash, Irrinki, Santosh, Subbiah Nagaraj, Satish, Kaman, Lileswar. (1403). 'Presentation and Outcomes of Patients with Colorectal Malignancies Undergoing Emergency Surgery – Experience from a Tertiary Care Centre in India', سامانه مدیریت نشریات علمی, 13(1), pp. 8-14. doi: 10.30476/acrr.2025.105365.1235
Sakaray, Yashwant, Maheshwari, Naveeen, Thakur, Manish, J, Sisira, Kurdia, Kailash, Irrinki, Santosh, Subbiah Nagaraj, Satish, Kaman, Lileswar. Presentation and Outcomes of Patients with Colorectal Malignancies Undergoing Emergency Surgery – Experience from a Tertiary Care Centre in India. سامانه مدیریت نشریات علمی, 1403; 13(1): 8-14. doi: 10.30476/acrr.2025.105365.1235

Presentation and Outcomes of Patients with Colorectal Malignancies Undergoing Emergency Surgery – Experience from a Tertiary Care Centre in India

Iranian Journal of Colorectal Research
مقاله 2، دوره 13، شماره 1، خرداد 2025، صفحه 8-14    اصل مقاله (555.07 K)
نوع مقاله: Research/Original Article
شناسه دیجیتال (DOI): 10.30476/acrr.2025.105365.1235
نویسندگان
Yashwant Sakaray* ؛ Naveeen Maheshwari؛ Manish Thakur؛ Sisira J؛ Kailash Chand Kurdia؛ Santosh Irrinki؛ Satish Subbiah Nagaraj؛ Lileswar Kaman
Post Graduate Institute of Medical Education and Research, Chandigarh
چکیده
 Background: Patients with colorectal cancer (CRC) presenting acutely to the emergency department vary in 
their physiological statuses and disease stages, necessitating a tailored surgical approach. This study assessed 
the presentation, surgical management, and perioperative outcomes of emergency CRC.
 Methods: A retrospective analysis was conducted on data collected from 44 patients presenting with acute 
CRC at the Postgraduate Institute of Medical Education and Research, Chandigarh, India, from January 2020 
to January 2022. Presentation, pathological, and surgical outcomes were assessed.
 Results: The mean age at presentation was 53.04±15.04 years (19-77). Intestinal obstruction was the most 
common presentation. A total of 24 colorectal resections (54.6%) were performed, along with 14 diversion 
colostomies (31.8%) and 6 diversion ileostomies (13.6%). The length of hospital stay (LOH) was 8.5±5.6 days, 
with a discharge rate of 77%. The 30-day mortality rate was 9.09%, and the readmission rate was 2.27%. A 
comparison of tumor resection versus non-resection procedures revealed statistically significant differences 
in mean age and LOH (P=0.019 and P=0.032, respectively). Tumor, Node, and Metastasis (TNM) staging was 
completed in 26 patients (56.5%); among them, 3 had stage I (11%), 8 had stage II (31%), 7 had stage III (27%), 
and 8 had stage IV (31%) disease. Among all patients, 23 (50%) had T3 disease, and 29 (63%) had moderately 
differentiated tumors. The median time to start adjuvant treatment was 3.5 months after surgery.
 Conclusion: This single-center retrospective study found that acute presentations of colorectal cancer in the 
emergency department were commonly associated with advanced-stage disease and significant physiological 
derangements. These factors presented considerable challenges to surgical approaches and perioperative 
management, potentially impacting long-term outcomes. Further studies are needed to assess the generalizability 
of these findings.

تازه های تحقیق

Yashwant Sakaray (Google Scholar)

کلیدواژه‌ها
Colorectal Cancer؛ Emergency؛ Outcomes؛ Acute؛ Surgery
مراجع
1. Sung H, Ferlay J, Siegel RL,
Laversanne M, Soerjomataram I,
Jemal A, et al. Global Cancer Statistics
2020: GLOBOCAN Estimates of
Incidence and Mortality Worldwide
for 36 Cancers in 185 Countries.
CA: a cancer journal for clinicians.
2021;71(3):209-49.
2. Vinay Mathew Thomas BB, Kevin
Wang, Feitong Lei, Quan Chen, Bin
Huang, and Aju Mathew. Trends
in colorectal cancer incidence in
India. Journal of Clinical Oncology.
2020;38(15).
3. Baer C, Menon R, Bastawrous
S, Bastawrous A. Emergency
Presentations of Colorectal Cancer.
The Surgical clinics of North
America. 2017;97(3):529-45.
4. van Hooft JE, Bemelman WA,
Oldenburg B, Marinelli AW, Lutke
Holzik MF, Grubben MJ, et al.
Colonic stenting versus emergency
surgery for acute left-sided malignant
colonic obstruction: a multicentre
randomised trial. The Lancet
Oncology. 2011;12(4):344-52.
5. Jeong DS, Kim YH, Kim KJ. Surgical
Outcomes and Risk Factors in
Patients Who Underwent Emergency
Colorectal Surgery. Annals of
coloproctology. 2017;33(6):239-44.
6. McBride R MC, Mulholland K.
Outcomes of emergency colorectal
surgery in a district general hospital.
Gut. 2015;64(171).
7. Lavanchy JL, Vaisnora L, Haltmeier
T, Zlobec I, Brügger LE, Candinas D,
et al. Oncologic long-term outcomes
of emergency versus elective resection
for colorectal cancer. International
journal of colorectal disease.
2019;34(12):2091-9.
8. Rabeneck L, Paszat LF, Li C. Risk
factors for obstruction, perforation, or
emergency admission at presentation
in patients with colorectal cancer:
a population-based study. The
American journal of gastroenterology.
2006;101(5):1098-103.
9. Norman J, Moodley Y. Large Bowel
Perforation in Patients with Colorectal
Cancer: A South African Perspective.
Journal of cancer & allied specialties.
2023;9(1):517.
10. Noronha J, deSouza A, Patil P,
Mehta S, Engineer R, Ostwal V, et
al. Management of colon cancer at
a tertiary referral center in India -
Patterns of presentation, treatment,
and survival outcomes. Indian journal
of cancer. 2019;56(4):297-301.
11. Lee S, Huh SJ, Oh SY, Koh MS, Kim
SH, Lee JH, et al. Clinical significance
of coagulation factors in operable
colorectal cancer. Oncology letters.
2017;13(6):4669-74.
12. Amer ican Society of
Anesthesiologists. ASA physical
status classification system. .
https://wwwasahqorg/standardsand-
guidelines/asa-physical-statusclassification-
system. 2020.
13. Dindo D, Demartines N, Clavien
PA. Classification of surgical
complications: a new proposal with
evaluation in a cohort of 6336 patients
and results of a survey. Annals of surgery. 2004;240(2):205-13.
14. Mun JY, Kim JE, Yoo N, Cho
HM, Kim H, An HJ, et al. Survival
Outcomes after Elective or Emergency
Surgery for Synchronous Stage IV
Colorectal Cancer. Biomedicines.
2022;10(12).
15. Golder AM, McMillan DC, Horgan
PG, Roxburgh CSD. Determinants
of emergency presentation in patients
with colorectal cancer: a systematic
review and meta-analysis. Scientific
reports. 2022;12(1):4366.
16. Talebreza A YE, Bolvardi E, Masoumi
B, Bahramian M, Darian EK.
Investigation of clinicopathological
parameters in emergency colorectal
cancer surgery: a study of 67 patients.
Arch Med Sci. 2017;13:1394-98.
17. Nguyen DA, Mai-Phan TA, Do
PTT, Thai TT. Emergency surgery
for obstructed colorectal cancer in
Vietnam. Asian journal of surgery.
2020;43(6):683-9.
18. Symeonidis D, Christodoulidis G,
Koukoulis G, Spyridakis M, Tepetes
K. Colorectal cancer surgery in the
elderly: limitations and drawbacks.
Techniques in coloproctology. 2011;15
Suppl 1:S47-50.
19. Tanis PJ, Paulino Pereira NR, van
Hooft JE, Consten EC, Bemelman WA.
Resection of Obstructive Left-Sided
Colon Cancer at a National Level: A
Prospective Analysis of Short-Term
Outcomes in 1,816 Patients. Digestive
surgery. 2015;32(5):317-24.
20. Ho YH, Siu SK, Buttner P, Stevenson
A, Lumley J, Stitz R. The effect of
obstruction and perforation on
colorectal cancer disease-free
survival. World journal of surgery.
2010;34(5):1091-101.
21. Wanis KN, Ott M, Van Koughnett
JAM, Colquhoun P, Brackstone M.
Long-term oncological outcomes
following emergency resection
of colon cancer. International
journal of colorectal disease.
2018;33(11):1525-32.
22. Ocak S, Bük Ö, Çiftci A, Yemez
K. Comparison Of Emergency
And Elective Colorectal Cancer
Surgery- A Single Center Experience.
Polski przeglad chirurgiczny.
2021;93(2):40-2.
23. Lavrijssen BDA, Ruiter R, Fest J,
Ikram MA, Stricker BH, van Eijck
CHJ. Trends in Staging, Treatment,
and Survival in Colorectal Cancer
Between 1990 and 2014 in the
Rotterdam Study. Frontiers in
oncology. 2022;12:849951

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