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Karahan, Furkan, Taş, Hüseyin. (1403). Relationship Between Gastric Helicobacter pylori Infection and Colorectal Polyps: A Retrospective Cohort Study. سامانه مدیریت نشریات علمی, 12(4), -. doi: 10.30476/acrr.2025.105645.1238
Furkan Karahan; Hüseyin Taş. "Relationship Between Gastric Helicobacter pylori Infection and Colorectal Polyps: A Retrospective Cohort Study". سامانه مدیریت نشریات علمی, 12, 4, 1403, -. doi: 10.30476/acrr.2025.105645.1238
Karahan, Furkan, Taş, Hüseyin. (1403). 'Relationship Between Gastric Helicobacter pylori Infection and Colorectal Polyps: A Retrospective Cohort Study', سامانه مدیریت نشریات علمی, 12(4), pp. -. doi: 10.30476/acrr.2025.105645.1238
Karahan, Furkan, Taş, Hüseyin. Relationship Between Gastric Helicobacter pylori Infection and Colorectal Polyps: A Retrospective Cohort Study. سامانه مدیریت نشریات علمی, 1403; 12(4): -. doi: 10.30476/acrr.2025.105645.1238

Relationship Between Gastric Helicobacter pylori Infection and Colorectal Polyps: A Retrospective Cohort Study

Iranian Journal of Colorectal Research
مقاله 3، دوره 12، شماره 4، اسفند 2024    اصل مقاله (817.97 K)
نوع مقاله: Research/Original Article
شناسه دیجیتال (DOI): 10.30476/acrr.2025.105645.1238
نویسندگان
Furkan Karahan* 1؛ Hüseyin Taş2
1Departman of General Surgery, Erciş State Hospital, Van, Turkey
2Departman of General Surgery, Izmir Katip Celebi University, Atatürk Education And Research Hospital, Izmir, Turkey
چکیده
Background: Infection with Helicobacter pylori (H. pylori) infection is one of the most prevalent bacterial
infections worldwide. It is well-established as a contributing factor to various conditions, including chronic
gastritis, peptic ulcers, and gastric cancer. This study aimed to investigate the potential association between H.
pylori infection and the presence of colorectal polyps.
Methods: This retrospective cohort study was conducted at the General Surgery Endoscopy Unit of İzmir Katip
Çelebi University between January 2019 and December 2022. Patients who underwent both gastroscopy and
colonoscopy were included in the study. The demographic data of the patients, along with their H. pylori status,
as well as the number, size, location, and pathology of any polyps, were recorded. A logistic regression model
was employed to analyze the relationship between the prevalence of H. pylori infection and the occurrence of
colorectal polyps.
Results: A total of 310 patients were included in the study, of whom 122 (39.4%) were men and 188 (60.6%)
were women. Colorectal polyps were identified in 133 cases, while 173 cases showed no evidence of polyps.
The rate of H. pylori infection was significantly higher in patients with colorectal polyps compared to those
without polyps (P<0.001). Furthermore, advanced age and the presence of multiple polyps were significantly
more prevalent in the H. pylori-positive group (P=0.002 and P=0.023, respectively). However, when polyps
were evaluated by size, location, type, and pathological subgroup, the rates of H. pylori infection did not differ
significantly between the groups. Similarly, when examining the type of adenoma and the degree of dysplasia,
H. pylori positivity showed no significant difference across the groups (P=0.742 and P=0.751, respectively).
Conclusion: The findings of our research imply that infection with H. pylori in the stomach may contribute to
a heightened likelihood of developing colorectal polyps. Therefore, individuals diagnosed with H. pylori might
gain preventive advantage from undergoing colonoscopic evaluation to detect polyps and mitigate the risk of
colorectal malignancy.
کلیدواژه‌ها
Polyps؛ Endoscopy؛ Helicobacter Pylori؛ Adenoma
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