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Melanosis Coli: Diagnosis, Clinical Significance, and Prognosis in Colorectal Screening | ||
| Iranian Journal of Colorectal Research | ||
| مقاله 5، دوره 12، شماره 4، اسفند 2024 اصل مقاله (2.25 M) | ||
| نوع مقاله: Case Report | ||
| شناسه دیجیتال (DOI): 10.30476/acrr.2025.105685.1240 | ||
| نویسندگان | ||
| Sahil C Sabharwal* 1؛ Kemmian Johnson2؛ Brandyn Young3؛ Sarah Assem1؛ Ragesh Thandassery2 | ||
| 1Department of Internal Medicine, University of Arkansas for Medical Sciences, Northwest Regional Campus, Fayetteville, Arkansas, United States | ||
| 2Department of Gastroenterology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States | ||
| 3University of Arkansas for Medical Sciences, College of Medicine, Fayetteville, Arkansas, United States | ||
| چکیده | ||
| Melanosis coli is a generally benign condition characterized by brown-black pigmentation of the colonic mucosa. It is classically associated with the prolonged use of anthraquinone laxatives, with senna and cascara being the most commonly utilized agents. The accumulation of the pigment lipofuscin within macrophages in the colonic lamina propria has been observed with long-term use of anthranoid laxatives. This phenomenon is consistent with the classic discoloration of the colon for which this condition is known, often observed during colonoscopy. The following case report focuses on a 55-year-old woman with a medical history that includes hypertension, uterine hypertrophy, menorrhagia, migraine, and constipation, who presented for a screening colonoscopy. It addresses the challenges in diagnosing melanosis coli and discusses its clinical significance based on a review of the relevant literature. This case review and literature search summarize information regarding the management and prognosis of melanosis coli in the context of colorectal cancer screening and the detection of adenomas. | ||
| کلیدواژه‌ها | ||
| Colonoscopy؛ Melanosis Coli؛ Screening Colonoscopy | ||
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آمار تعداد مشاهده مقاله: 38 تعداد دریافت فایل اصل مقاله: 43 |
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