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Melanosis Coli: Diagnosis, Clinical Significance, and Prognosis in Colorectal Screening | ||
| Iranian Journal of Colorectal Research | ||
| مقاله 5، دوره 12، شماره 4، اسفند 2024، صفحه 128-132 اصل مقاله (2.25 M) | ||
| نوع مقاله: Case Report | ||
| شناسه دیجیتال (DOI): 10.30476/acrr.2025.105685.1240 | ||
| نویسندگان | ||
| Sahil C Sabharwal* 1؛ Kemmian Johnson2؛ Brandyn Young3؛ Sarah Assem1؛ Ragesh Thandassery2 | ||
| 1Department of Internal Medicine, University of Arkansas for Medical Sciences, Northwest Regional Campus, Fayetteville, Arkansas, United States | ||
| 2Department of Gastroenterology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States | ||
| 3University of Arkansas for Medical Sciences, College of Medicine, Fayetteville, Arkansas, United States | ||
| چکیده | ||
| Melanosis coli is a generally benign condition characterized by brown-black pigmentation of the colonic mucosa. It is classically associated with the prolonged use of anthraquinone laxatives, with senna and cascara being the most commonly utilized agents. The accumulation of the pigment lipofuscin within macrophages in the colonic lamina propria has been observed with long-term use of anthranoid laxatives. This phenomenon is consistent with the classic discoloration of the colon for which this condition is known, often observed during colonoscopy. The following case report focuses on a 55-year-old woman with a medical history that includes hypertension, uterine hypertrophy, menorrhagia, migraine, and constipation, who presented for a screening colonoscopy. It addresses the challenges in diagnosing melanosis coli and discusses its clinical significance based on a review of the relevant literature. This case review and literature search summarize information regarding the management and prognosis of melanosis coli in the context of colorectal cancer screening and the detection of adenomas. | ||
تازه های تحقیق | ||
Sahil Sabharwal (Google Scholar) | ||
| کلیدواژه‌ها | ||
| Colonoscopy؛ Melanosis Coli؛ Screening Colonoscopy | ||
| مراجع | ||
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1. Ezike, K., Okwudire-Ejeh, I., Salu, I., Nnabuchi, C., Aghahowa, M. E., Ani, F. O., & Isaac, H. M. (2023). Biopsy-proven melanosis coli initially diagnosed as candidiasis on colonoscopy: A report of two cases from North Central Nigeria. Cureus. 2. Kuriyama, A. (2021). Melanosis coli. JMA Journal. 3. Blackett, J. W., Rosenberg, R., Mahadev, S., Green, P. H. R., & Lebwohl, B. (2018). Adenoma Detection is Increased in the Setting of Melanosis Coli. Journal of clinical gastroenterology, 52(4), 313–318. https://doi.org/10.1097/ MCG.0000000000000756 4. Tsobanidou C.h (2005). Melanosis coli in two patients with colorectal neoplasia. Journal of B.U.ON. : official journal of the Balkan Union of Oncology, 10(1), 131–133. 5. Nusko, G., Schneider, B., Ernst, H., Wittekind, C., & Hahn, E. G. (1997). Melanosis coli--a harmless pigmentation or a precancerous condition?. Zeitschrift fur Gastroenterologie, 35(5), 313–318. 6. Blackett, J. W., Rosenberg, R., Mahadev, S., Green, P., & Lebwohl, B. (2016). Adenoma detection is increased in the setting of melanosis coli. Journal of Clinical Gastroenterology. 7. Abu Baker, F., Mari, A., Feldman, D., Suki, M., Gal, O., & Kopelman, Y. (2018). Melanosis coli: A helpful contrast effect or a harmful pigmentation? Clinical Medicine Insights: Gastroenterology. 8. Kew, S., & Chakravarthi, S. (2013). Images in clinical medicine: Melanosis coli. The New England Journal of Medicine. 9. Lo, C. M., Chen, C. C., Yeh, Y. H., Chang, C., & Yeh, H. J. (2020). Quantitative analysis of melanosis coli colonic mucosa using textural patterns. Applied Sciences. 10. Zapatier, J., Schneider, A., & Parra, J. (2010). Overestimation of ulcerative colitis due to melanosis coli. Acta Gastroenterologica Latinoamericana. 11. Kassim, S. A., Abbas, M., Tang, W., Wu, S., Meng, Q., Zhang, C., Naeem, S., Li, X., & Chen, R. (2019). Retrospective study on melanosis coli as risk factor of colorectal neoplasm: A 3-year colonoscopic finding in Zhuhai Hospital, China. International Journal of Colorectal Disease. | ||
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آمار تعداد مشاهده مقاله: 66 تعداد دریافت فایل اصل مقاله: 67 |
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