LinkedIn

 آمار

تعداد نشریات20
تعداد شماره‌ها1,212
تعداد مقالات11,048
تعداد مشاهده مقاله74,676,451
تعداد دریافت فایل اصل مقاله98,347,522
Mehdizadeh, Mohammad, Lotfi, Ali, Atarbashi-Moghadam, Saede, Eftekhari-Moghadam, Parsa. (1404). Mandibular Metastatic Breast Cancer: A Rare Case Report with Diagnostic Challenge. سامانه مدیریت نشریات علمی, 26(3), 284-287. doi: 10.30476/dentjods.2025.103764.2475
Mohammad Mehdizadeh; Ali Lotfi; Saede Atarbashi-Moghadam; Parsa Eftekhari-Moghadam. "Mandibular Metastatic Breast Cancer: A Rare Case Report with Diagnostic Challenge". سامانه مدیریت نشریات علمی, 26, 3, 1404, 284-287. doi: 10.30476/dentjods.2025.103764.2475
Mehdizadeh, Mohammad, Lotfi, Ali, Atarbashi-Moghadam, Saede, Eftekhari-Moghadam, Parsa. (1404). 'Mandibular Metastatic Breast Cancer: A Rare Case Report with Diagnostic Challenge', سامانه مدیریت نشریات علمی, 26(3), pp. 284-287. doi: 10.30476/dentjods.2025.103764.2475
Mehdizadeh, Mohammad, Lotfi, Ali, Atarbashi-Moghadam, Saede, Eftekhari-Moghadam, Parsa. Mandibular Metastatic Breast Cancer: A Rare Case Report with Diagnostic Challenge. سامانه مدیریت نشریات علمی, 1404; 26(3): 284-287. doi: 10.30476/dentjods.2025.103764.2475

Mandibular Metastatic Breast Cancer: A Rare Case Report with Diagnostic Challenge

Journal of Dentistry
مقاله 34، دوره 26، شماره 3 - شماره پیاپی 88، آذر 2025، صفحه 284-287    اصل مقاله (382.2 K)
نوع مقاله: Case Report
شناسه دیجیتال (DOI): 10.30476/dentjods.2025.103764.2475
نویسندگان
Mohammad Mehdizadeh1؛ Ali Lotfi2؛ Saede Atarbashi-Moghadam* 2؛ Parsa Eftekhari-Moghadam3
1Dept. of Oral and Maxillofacial Surgery, School of Dentistry, Qom University of Medical Sciences, Qom, Iran.
2Dept. of Oral and Maxillofacial Pathology, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
3Undergraduate Student, Research Committee, School of Dentistry, Shahid Beheshti, University of Medical Sciences, Tehran, Iran.
چکیده
Jawbone metastatic lesions are a diagnostic challenge because of their rarity and variable clinical, radiographic, and histopathologic characteristics. This paper presents a 57-year-old female with a chief complaint of lower face swelling. Cone beam computed tomography (CBCT) showed a multilocular radiolucency with right angle septa in the left mandibular area with cortical destruction. She had a history of right breast cancer about six years ago. Histopathologic examination revealed sheets of malignant small round cells. Immunohistochemistry (IHC) was only positive for cytokeratin (CK) and GATA3. CA15-3 tumor marker was higher than the normal range. Based on the aforementioned data, the diagnosis of metastatic breast carcinoma was performed. The whole-body and computed tomography (CT) scan showed just involvement in the left mandibular area. The radiographic appearance of metastatic lesions might be misleading, and microscopic sections might be poorly differentiated, therefore, a precise past medical history, IHC staining, and tumor markersre valuable issues in diagnosing oral cavity metastasis.

تازه های تحقیق

Saede Atarbashi Moghadam (Google Scholar)

کلیدواژه‌ها
Metastasis؛ Breast cancer؛ Mandible؛ Oral cavity
مراجع
  • Waknis P, Limaye G, Mahajan M, Joshi S. A case of an undiagnosed metastasized breast cancer mimicking odontogenic cyst-a diagnostic challenge. J Maxillofac Oral Surg. 2023; 22: 136-140.
  • Ho DP, Wilkinson PE, Vogel RI, Gopalakrishnan R, Argyris PP. Metastatic tumors to the oral soft tissues and jawbones: A retrospective analysis of 40 cases and review of the Literature. Head Neck Patho. 2022; 16: 802-813.
  • Sadri D, Azizi A, Farhadi S, Shokrgozar H, Entezari N. Head and neck metastatic tumors: a retrospective survey of Iranian patients. J Dent (Shiraz). 2015; 16: 17-21.
  • Atarbashi-Moghadam S, Jafarian M, Dowdani S. Metastatic Adenocarcinoma of Mandible with Unknown Primary Origin (CUP Syndrome): a Rare Case Report. J Dent (Shiraz). 2023; 24: 444-448.
  • Atarbashi-Moghadam S, Atarbashi-Moghadam F, Niazmand M, Shahrabi-Farahani S. Metastatic sarcomas of the oral cavity: A systematic review. J Stomatol Oral Maxillofac Surg. 2024; 125: 101656.
  • Shibuya R, Matsuyama A, Nakamoto M, Shiba E, Kasai T, Hisaoka M. The combination of CD99 and NKX2.2, a transcriptional target of EWSR1-FLI1, is highly specific for the diagnosis of Ewing sarcoma. Virchows Arch. 2014; 465: 599-605.
  • Chen S, Deniz K, Sung YS, Zhang L, Dry S, Antonescu CR. Ewing sarcoma with ERG gene rearrangements: A molecular study focusing on the prevalence of FUS-ERG and common pitfalls in detecting EWSR1-ERG fusions by FISH. Genes Chromosomes Cancer. 2016; 55: 340-349.
  • Nel C, Uys A, Robinson L, Nortjé CJ. Radiological spectrum of metastasis to the oral and maxillofacial region. Oral Radiol. 2022; 38: 37-48.
  • Pavlidis N, Pentheroudakis G. Cancer of unknown primary site. Lancet. 2012; 379(9824): 1428-1435.
  • Fakhari A, Gharepapagh E, Dabiri S, Gilani N. Correlation of cancer antigen 15-3 (CA15-3) serum level and bony metastases in breast cancer patients. Med J Islam Repub Iran. 2019; 33: 142.
  • Varghese G, Singh SP, Sreela LS. A rare case of breast carcinoma metastasis to mandible and vertebrae. Natl J Maxillofac Surg. 2014; 5: 184-187.
  • Miyazaki R, Kimoto N, Okamoto S, Tsuji A, Nishigushi Y, Miyahara T, et al. Breast carcinoma metastasis to the cheek: a case report. J Med Case Rep. 2022; 16: 108.
  • Cai Z, Zhu C, Wang L, Zhu L, Zhang Z, Zhu H, Wang Y. A retrospective study of six patients with mandibular metastatic carcinoma. Oncol Lett. 2016; 11: 3650-3654.
آمار
تعداد مشاهده مقاله: 170
تعداد دریافت فایل اصل مقاله: 114


سامانه مدیریت نشریات علمی. قدرت گرفته از سیناوب