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Clinical and Epidemiological Profiles of Colorectal Cancer Patients Diagnosed on Colonoscopy in Nigeria | ||
| Iranian Journal of Colorectal Research | ||
| مقاله 2، دوره 12، شماره 3، آذر 2024، صفحه 70-77 اصل مقاله (1.89 M) | ||
| نوع مقاله: Research/Original Article | ||
| شناسه دیجیتال (DOI): 10.30476/acrr.2024.102111.1211 | ||
| نویسندگان | ||
| Yusuf Musa* 1؛ Pantong Mark Davwar2؛ Kenechukwu Chukwuemeka Okonkwo3؛ Lukman O Abdulkareem4؛ Matthew Olumuyiwa Bojuwoye5؛ Opeyemi Owoseni6؛ Chinwe Onyia7؛ Yusuf Shehu Umar8؛ Kolawole Oluseyi Akande9 | ||
| 1Gastroenterology Unit, Department of Internal Medicine, Federal Teaching Hospital Katsina, Nigeria | ||
| 2Department of Medicine, Jos University Teaching Hospital, Jos Nigeria | ||
| 3Department of Medicine, Federal Medical Centre, Owo Nigeria | ||
| 4Department of Medicine, University of Abuja Teaching Hospital, Abuja Nigeria | ||
| 5Department of Medicine, University of Ilorin, Ilorin Nigeria | ||
| 6Department of Medicine, Federal Medical Centre Abeokuta, Abeokuta Nigeria | ||
| 7Department of Medicine, University of Nigeria Teaching Hospital, Enugu Nigeria. | ||
| 8Department of Medicine, Murtala Muhammad Specialist Hospital, Kano Nigeria. | ||
| 9Department of Internal Medicine, College of Medicine, University of Ibadan, Oyo State Nigeria. | ||
| چکیده | ||
| Background: Colorectal cancer (CRC) is the third most common cancer globally, and the second most common cause of cancer death. CRC incidence is increasing in Nigeria, while its national demographic data distribution is limited. This study aims to determine the frequency of CRC found on colonoscopies in various parts of Nigeria. Methods: This was a retrospective study of CRCs diagnosed in Nigeria between 2021 and 2023. Data from endoscopy registers include patients’ demographics, regional location, preparation, scope used, tumour location, and histology. A Google form was used for data collection from all contributors. Data was analysed using SPSS version 20, means and standard deviations were used to summarise continuous variables, while frequencies and percentages were used for categorical variables. Categorical variables were compared using chi-square or Fisher exact tests. P values less than 0.05 were considered significant. Results: A total of 2387 procedures were performed in 8 centres. Epsom salt with Dulcolax was the most commonly used cleansing agent with an average preparation score of 6.6. A total of 322 patients had suspected colonic tumour with a prevalence of 13.5%. After censoring for missing data, a total of 272 patients were analysed. The mean age ± standard deviation was 56.3 ± 15.5 years. Females were 53.3% with a M: F ratio of 1:1.14. A statistically significant difference was observed between genders across the country regions (P = 0.013). The most common indication was bleeding pre-rectum (38.24%) while screening colonoscopy was done only in 10 (3.8%). The most common tumour location was a recto-sigmoid colon (48.16%), while the commonest tumour histology was adenocarcinoma. Conclusion: Our study provides data on the prevalence of colon cancer in Nigeria. The findings suggest rectal bleeding is an important warning feature. This emphasizes the need for early detection of average-risk individuals and prompt treatment of cases. | ||
تازه های تحقیق | ||
Musa Yusuf (Google Scholar) | ||
| کلیدواژه‌ها | ||
| Screening Colonoscopy؛ Early Cancer Detection؛ Bleeding Per Rectum؛ Adenocarcinoma | ||
| مراجع | ||
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آمار تعداد مشاهده مقاله: 168 تعداد دریافت فایل اصل مقاله: 226 |
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