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Immunohistochemical Analysis of Oral Spindle Cell Hemangioma | ||
| Journal of Dentistry | ||
| مقاله 12، دوره 26، شماره 2 - شماره پیاپی 87، شهریور 2025، صفحه 194-198 اصل مقاله (370.67 K) | ||
| نوع مقاله: Case Report | ||
| شناسه دیجیتال (DOI): 10.30476/dentjods.2024.101499.2305 | ||
| نویسندگان | ||
| Amit Mani1؛ Manas Bajpai* 2؛ Saurabh Sabnis2 | ||
| 1Dept. of Periodontology, Pravara Institute of Medical Sciences, Rural Dental College Loni (Maharashtra) India. | ||
| 2Dept. of Oral Pathology and Microbiology, Pravara Institute of Medical Sciences, Rural Dental College Loni (Maharashtra) India. | ||
| چکیده | ||
| Spindle cell hemangioma (SCH), formerly called “spindle cell hemangioendothelioma”, is a rare benign histological variant of hemangioma characterized by the presence of two contrast zones, the first zone exhibits large dilated cavernous space with slit-like vascular spaces may show clear endothelial vacuoles resembling fat cells. SCH is often considered as pseudosarcomatous entity; it imposes a diagnostic challenge for oral pathologists due to its resemblance with Kaposi sarcoma. A total of 13 cases of SCH have been reported in the head and neck region to date and only 6 cases have been reported inside the oral cavity. We present a rare case of SCH located on the hard palate, which imitated Kaposi's sarcoma on histopathological examination. The expressions of various markers including EGR, CD 31, and HHV 8 yielded the final diagnosis of SCH. The markers EGR and HHV 8 have never been used in intraoral SCH before to the best of our knowledge; hence, the present report highlights the use of immunohistochemistry for the diagnosis of SCH. | ||
| کلیدواژه‌ها | ||
| Hemangioma؛ Immunohistochemistry؛ Hemangioendothelioma؛ Palate | ||
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آمار تعداد مشاهده مقاله: 219 تعداد دریافت فایل اصل مقاله: 232 |
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