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Mortazavi, Seyed Ali Reza, Jafarzadeh, Abdollah, Ghadimi-Moghadam, Abdolkarim, Mortazavi, Seyed Mohammad Javad, Haghani, Masoud, Ghadimi-Moghadam, Ali, Sihver, Lembit. (1404). Breakthrough Infection and Death after COVID-19 Vaccination: A Physics Perspective. سامانه مدیریت نشریات علمی, 15(3), 299-306. doi: 10.31661/jbpe.v0i0.2212-1577
Seyed Ali Reza Mortazavi; Abdollah Jafarzadeh; Abdolkarim Ghadimi-Moghadam; Seyed Mohammad Javad Mortazavi; Masoud Haghani; Ali Ghadimi-Moghadam; Lembit Sihver. "Breakthrough Infection and Death after COVID-19 Vaccination: A Physics Perspective". سامانه مدیریت نشریات علمی, 15, 3, 1404, 299-306. doi: 10.31661/jbpe.v0i0.2212-1577
Mortazavi, Seyed Ali Reza, Jafarzadeh, Abdollah, Ghadimi-Moghadam, Abdolkarim, Mortazavi, Seyed Mohammad Javad, Haghani, Masoud, Ghadimi-Moghadam, Ali, Sihver, Lembit. (1404). 'Breakthrough Infection and Death after COVID-19 Vaccination: A Physics Perspective', سامانه مدیریت نشریات علمی, 15(3), pp. 299-306. doi: 10.31661/jbpe.v0i0.2212-1577
Mortazavi, Seyed Ali Reza, Jafarzadeh, Abdollah, Ghadimi-Moghadam, Abdolkarim, Mortazavi, Seyed Mohammad Javad, Haghani, Masoud, Ghadimi-Moghadam, Ali, Sihver, Lembit. Breakthrough Infection and Death after COVID-19 Vaccination: A Physics Perspective. سامانه مدیریت نشریات علمی, 1404; 15(3): 299-306. doi: 10.31661/jbpe.v0i0.2212-1577

Breakthrough Infection and Death after COVID-19 Vaccination: A Physics Perspective

Journal of Biomedical Physics and Engineering
مقاله 10، دوره 15، شماره 3 - شماره پیاپی 1، شهریور 2025، صفحه 299-306    اصل مقاله (641.97 K)
نوع مقاله: Commentary
شناسه دیجیتال (DOI): 10.31661/jbpe.v0i0.2212-1577
نویسندگان
Seyed Ali Reza Mortazavi1؛ Abdollah Jafarzadeh2؛ Abdolkarim Ghadimi-Moghadam3؛ Seyed Mohammad Javad Mortazavi4؛ Masoud Haghani5؛ Ali Ghadimi-Moghadam6؛ Lembit Sihver* 7، 8، 9
1MVLS College, The University of Glasgow, Glasgow, Scotland, UK
2Department of Immunology, Faculty of Medicine, Kerman University of Medical Sciences, Kerman, Iran
3Yasuj University of Medical Sciences, Yasuj, Iran
4Department of Medical Physics and Engineering, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
5Department of Radiology, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran
6Faculty of Medicine, Szeged University, Szeged, Hungary
7Department of Informatics and Engineering Systems, College of Engineering and Computer Science, University of Texas Rio Grande Valley, TX, USA
8Department of Chemistry and Chemical Engineering, Royal Military College of Canada, Kingston, ON, Canada
9Department of Physics, East Carolina University, Greenville, NC 27858, USA
چکیده
The largest universal immunization in history has occurred as a result of the COVID-19 pandemic. The developed COVID-19 vaccines have been shown to provide protection against severe forms of COVID-19 by inducing anti-spike neutralizing antibodies. It has been found that individuals who have not been vaccinated against COVID-19 were more likely to contract the virus during a period when the Delta variant was dominant, as compared to those who have received the complete dose of the vaccine, irrespective of the variant. However, there is no notable disparity in the likelihood of hospitalization, requirement for mechanical ventilation, or mortality between the two groups once infected. Nevertheless, those who are unvaccinated may require additional oxygen support. There are reports indicating unfavorable health effects, ranging from transient thyroid dysfunction to death following vaccination. In addition, some people are susceptible to SARS-CoV-2 infection despite they have immunized with the COVID-19 vaccine. Given all these considerations, several key factors should be better understood and considered to enable us to even more successfully manage future pandemics breakthrough infections. The effectiveness of physical treatment methods, e.g., Low Dose Radiation Therapy (LDRT) should be compared to pharmacological treatments.

تازه های تحقیق

Lembit Sihver (Google Scholar)

کلیدواژه‌ها
COVID-19؛ SARS-CoV-2؛ Vaccines؛ Cytokine Storm؛ Medical Physics
مراجع
  1. Shiravi AA, Ardekani A, Sheikhbahaei E, Heshmat-Ghahdarijani K. Cardiovascular Complications of SARS-CoV-2 Vaccines: An Overview. Cardiol Ther. 2022;11(1):13-21. doi: 10.1007/s40119-021-00248-0. PubMed PMID: 34845662. PubMed PMCID: PMC8629102.
  2. Aerts S, Deschrijver D, Joseph W, Verloock L, Goeminne F, Martens L, Dhaene T. Exposure assessment of mobile phone base station radiation in an outdoor environment using sequential surrogate modeling. Bioelectromagnetics. 2013;34(4):300-11. doi: 10.1002/bem.21764. PubMed PMID: 23315952.
  3. Keyhani A, Sharifi I, Salarkia E, Khosravi A, Tavakoli Oliaee R, et al. In vitro and in vivo therapeutic potentials of 6-gingerol in combination with amphotericin B for treatment of Leishmania major infection: Powerful synergistic and multifunctional effects. Int Immunopharmacol. 2021;101(Pt B):108274. doi: 10.1016/j.intimp.2021.108274. PubMed PMID: 34688150.
  4. Kyriakidis NC, López-Cortés A, González EV, Grimaldos AB, Prado EO. SARS-CoV-2 vaccines strategies: a comprehensive review of phase 3 candidates. NPJ Vaccines. 2021;6(1):28. doi: 10.1038/s41541-021-00292-w. PubMed PMID: 33619260. PubMed PMCID: PMC7900244.
  5. Jafarzadeh A, Nemati M, Jafarzadeh S, Nozari P, Mortazavi SMJ. Thyroid dysfunction following vaccination with COVID-19 vaccines: a basic review of the preliminary evidence. J Endocrinol Invest. 2022;45(10):1835-63. doi: 10.1007/s40618-022-01786-7. PubMed PMID: 35347651. PubMed PMCID: PMC8960081.
  6. Shafie’ei M, Jamali M, Akbari Z, Sarvipour N, Ahmadzade M, Ahramiyanpour N. Cutaneous adverse reactions following COVID-19 vaccinations: A systematic review and meta-analysis. J Cosmet Dermatol. 2022;21(9):3636-50. doi: 10.1111/jocd.15261. PubMed PMID: 35861631. PubMed PMCID: PMC9350270.
  7. Jafarzadeh A, Jafarzadeh S, Pardehshenas M, Nemati M, Mortazavi SMJ. Development and exacerbation of autoimmune hemolytic anemia following COVID-19 vaccination: A systematic review. Int J Lab Hematol. 2023;45(2):145-55. doi: 10.1111/ijlh.13978. PubMed PMID: 36208056. PubMed PMCID: PMC9874780.
  8. Hosseinzadeh A, Sahab-Negah S, Nili S, Aliyari R, Goli S, Fereidouni M, et al. COVID-19 cases, hospitalizations and deaths after vaccination: a cohort event monitoring study, Islamic Republic of Iran. Bull World Health Organ. 2022;100(8):474-83. doi: 10.2471/BLT.22.288073. PubMed PMID: 35923277. PubMed PMCID: PMC9306382.
  9. Arora G, Taneja J, Bhardwaj P, Goyal S, Naidu K, Yadav SK, et al. Adverse events and breakthrough infections associated with COVID-19 vaccination in the Indian population. J Med Virol. 2022;94(7):3147-54. doi: 10.1002/jmv.27708. PubMed PMID: 35261064. PubMed PMCID: PMC9088477.
  10. Jafarzadeh A, Chauhan P, Saha B, Jafarzadeh S, Nemati M. Contribution of monocytes and macrophages to the local tissue inflammation and cytokine storm in COVID-19: Lessons from SARS and MERS, and potential therapeutic interventions. Life Sci. 2020;257:118102. doi: 10.1016/j.lfs.2020.118102. PubMed PMID: 32687918. PubMed PMCID: PMC7367812.
  11. Zimmermann P, Curtis N. Factors That Influence the Immune Response to Vaccination. Clin Microbiol Rev. 2019;32(2):e00084-18. doi: 10.1128/CMR.00084-18. PubMed PMID: 30867162. PubMed PMCID: PMC6431125.
  12. Semenzato L, Botton J, Drouin J, Baricault B, Bertrand M, Jabagi MJ, et al. Characteristics associated with the residual risk of severe COVID-19 after a complete vaccination schedule: A cohort study of 28 million people in France. Lancet Reg Health Eur. 2022;19:100441. doi: 10.1016/j.lanepe.2022.100441. PubMed PMID: 35789881. PubMed PMCID: PMC9243470.
  13. Jafarzadeh A, Gosain R, Mortazavi SMJ, Nemati M, Jafarzadeh S, Ghaderi A. SARS-CoV-2 Infection: A Possible Risk Factor for Incidence and Recurrence of Cancers. Int J Hematol Oncol Stem Cell Res. 2022;16(2):117-27. doi: 10.18502/ijhoscr.v16i2.9205. PubMed PMID: 36304732. PubMed PMCID: PMC9547773.
  14. Lee LYW, Starkey T, Ionescu MC, Little M, Tilby M, Tripathy AR, et al. Vaccine effectiveness against COVID-19 breakthrough infections in patients with cancer (UKCCEP): a population-based test-negative case-control study. Lancet Oncol. 2022;23(6):748-57. doi: 10.1016/S1470-2045(22)00202-9. PubMed PMID: 35617989. PubMed PMCID: PMC9126559.
  15. Abu-Raddad LJ, Chemaitelly H, Ayoub HH, Yassine HM, Benslimane FM, Al Khatib HA, et al. Association of Prior SARS-CoV-2 Infection With Risk of Breakthrough Infection Following mRNA Vaccination in Qatar. 2021;326(19):1930-9. doi: 10.1001/jama.2021.19623. PubMed PMID: 34724027. PubMed PMCID: PMC8561432.
  16. Amanatidou E, Gkiouliava A, Pella E, Serafidi M, Tsilingiris D, Vallianou NG, et al. Breakthrough infections after COVID-19 vaccination: Insights, perspectives and challenges. Metabol Open. 2022;14:100180. doi: 10.1016/j.metop.2022.100180. PubMed PMID: 35313532. PubMed PMCID: PMC8928742.
  17. Kliker L, Zuckerman N, Atari N, Barda N, Gilboa M, Nemet I, et al. COVID-19 vaccination and BA.1 breakthrough infection induce neutralising antibodies which are less efficient against BA.4 and BA.5 Omicron variants, Israel, March to June 2022. Euro Surveill. 2022;27(30):2200559. doi: 10.2807/1560-7917.ES.2022.27.30.2200559. PubMed PMID: 35904058. PubMed PMCID: PMC9336169.
  18. Van Beusekom M. Vaccines lower risk of long COVID 15%, death by 34%, data show. CIDRAP News; Minneapolis: Center for Infectious Disease Research and Policy (CIDRAP); 2022.
  19. Lee CJ, Woo W, Kim AY, Yon DK, Lee SW, Koyanagi A, et al. Clinical manifestations of COVID-19 breakthrough infections: A systematic review and meta-analysis. J Med Virol. 2022;94(9):4234-45. doi: 10.1002/jmv.27871. PubMed PMID: 35588301. PubMed PMCID: PMC9348075.
  20. Murata K, Nakao N, Ishiuchi N, Fukui T, Katsuya N, Fukumoto W, et al. Four cases of cytokine storm after COVID-19 vaccination: Case report. Front Immunol. 2022;13:967226. doi: 10.3389/fimmu.2022.967226. PubMed PMID: 36045681. PubMed PMCID: PMC9420842.
  21. Oberemok VV, Laikova KV, Yurchenko KA, Fomochkina II, Kubyshkin AV. SARS-CoV-2 will continue to circulate in the human population: an opinion from the point of view of the virus-host relationship. Inflamm Res. 2020;69(7):635-40. doi: 10.1007/s00011-020-01352-y. PubMed PMID: 32350571. PubMed PMCID: PMC7190393.
  22. Bevelacqua JJ, Mortazavi SMJ. Don’t worry! The next generation would be more resistant to SARS-CoV-2. Inflamm Res. 2020;69(12):1159-61. doi: 10.1007/s00011-020-01405-2. PubMed PMID: 32989506. PubMed PMCID: PMC7521771.
  23. Catanzaro M, Fagiani F, Racchi M, Corsini E, Govoni S, Lanni C. Immune response in COVID-19: addressing a pharmacological challenge by targeting pathways triggered by SARS-CoV-2. Signal Transduct Target Ther. 2020;5(1):84. doi: 10.1038/s41392-020-0191-1. PubMed PMID: 32467561. PubMed PMCID: PMC7255975.
  24. Kupferschmidt K. The pandemic virus is slowly mutating. But is it getting more dangerous? News; Science; 2020.
  25. Meyerowitz EA, Richterman A, Gandhi RT, Sax PE. Transmission of SARS-CoV-2: A Review of Viral, Host, and Environmental Factors. Ann Intern Med. 2021;174(1):69-79. doi: 10.7326/M20-5008. PubMed PMID: 32941052. PubMed PMCID: PMC7505025.
  26. Welsh JS, Bevelacqua JJ, Mozdarani H, Mortazavi SA, Mortazavi SM. Why can COVID-19 fatality in space be significantly higher than on Earth? International Journal of Radiation Research. 2020;18(3):421-6.
  27. Rödel F, Arenas M, Ott OJ, Fournier C, Georgakilas AG, Tapio S, et al. Low-dose radiation therapy for COVID-19 pneumopathy: what is the evidence? Strahlenther Onkol. 2020;196(8):679-82. doi: 10.1007/s00066-020-01635-7. PubMed PMID: 32388805. PubMed PMCID: PMC7211051.
  28. Jafarzadeh A, Nemati M, Jafarzadeh S. Contribution of STAT3 to the pathogenesis of COVID-19. Microb Pathog. 2021;154:104836. doi: 10.1016/j.micpath.2021.104836. PubMed PMID: 33691172. PubMed PMCID: PMC7937040.
  29. Calabrese EJ, Dhawan G. How radiotherapy was historically used to treat pneumonia: could it be useful today? Yale J Biol Med. 2013;86(4):555-70. PubMed PMID: 24348219. PubMed PMCID: PMC3848110.
  30. Schröder S, Kriesen S, Paape D, Hildebrandt G, Manda K. Modulation of Inflammatory Reactions by Low-Dose Ionizing Radiation: Cytokine Release of Murine Endothelial Cells Is Dependent on Culture Conditions. J Immunol Res. 2018;2018:2856518. doi: 10.1155/2018/2856518. PubMed PMID: 29967799. PubMed PMCID: PMC6008836.
  31. Rödel F, Frey B, Manda K, Hildebrandt G, Hehlgans S, Keilholz L, et al. Immunomodulatory properties and molecular effects in inflammatory diseases of low-dose x-irradiation. Front Oncol. 2012;2:120. doi: 10.3389/fonc.2012.00120. PubMed PMID: 23057008. PubMed PMCID: PMC3457026.
  32. Yang G, Kong Q, Wang G, Jin H, Zhou L, Yu D, Niu C, Han W, et al. Low-dose ionizing radiation induces direct activation of natural killer cells and provides a novel approach for adoptive cellular immunotherapy. Cancer Biother Radiopharm. 2014;29(10):428-34. doi: 10.1089/cbr.2014.1702. PubMed PMID: 25402754. PubMed PMCID: PMC4267769.
  33. Hekim N, Cetin Z, Nikitaki Z, Cort A, Saygili EI. Radiation triggering immune response and inflammation. Cancer Lett. 2015;368(2):156-63. doi: 10.1016/j.canlet.2015.04.016. PubMed PMID: 25911239.
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