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Salari, Sina, Darakhshandeh, Ali, Gholampour Shahaboddini, Roohollah, Moghaddas, Azadeh. (1398). A Rare Presentation of Acute Myelogenous Leukemia: A Case Report of Vaginal and Uterine Myeloid Sarcoma from Iran. سامانه مدیریت نشریات علمی, 10(3), 263-269. doi: 10.30476/mejc.2019.78601.
Sina Salari; Ali Darakhshandeh; Roohollah Gholampour Shahaboddini; Azadeh Moghaddas. "A Rare Presentation of Acute Myelogenous Leukemia: A Case Report of Vaginal and Uterine Myeloid Sarcoma from Iran". سامانه مدیریت نشریات علمی, 10, 3, 1398, 263-269. doi: 10.30476/mejc.2019.78601.
Salari, Sina, Darakhshandeh, Ali, Gholampour Shahaboddini, Roohollah, Moghaddas, Azadeh. (1398). 'A Rare Presentation of Acute Myelogenous Leukemia: A Case Report of Vaginal and Uterine Myeloid Sarcoma from Iran', سامانه مدیریت نشریات علمی, 10(3), pp. 263-269. doi: 10.30476/mejc.2019.78601.
Salari, Sina, Darakhshandeh, Ali, Gholampour Shahaboddini, Roohollah, Moghaddas, Azadeh. A Rare Presentation of Acute Myelogenous Leukemia: A Case Report of Vaginal and Uterine Myeloid Sarcoma from Iran. سامانه مدیریت نشریات علمی, 1398; 10(3): 263-269. doi: 10.30476/mejc.2019.78601.

A Rare Presentation of Acute Myelogenous Leukemia: A Case Report of Vaginal and Uterine Myeloid Sarcoma from Iran

Middle East Journal of Cancer
مقاله 12، دوره 10، شماره 3 - شماره پیاپی 39، مهر 2019، صفحه 263-269    اصل مقاله (2.6 M)
نوع مقاله: Case Report(s)
شناسه دیجیتال (DOI): 10.30476/mejc.2019.78601.
نویسندگان
Sina Salari1؛ Ali Darakhshandeh2؛ Roohollah Gholampour Shahaboddini3؛ Azadeh Moghaddas* 4
1Department of Medical Oncology- Hematology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2Department of Medical Oncology- Hematology, Isfahan University of Medical Sciences, Isfahan, Iran
3Department of Pathology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
4Department of Clinical Pharmacy, Faculty of Pharmacy, Isfahan University of Medical Sciences, Isfahan, Iran
چکیده
Myeloid or granulocytic sarcoma is an extramedullary tumor of immature granulocytic cells. This condition is rare and has a challenging diagnosis, relying on a high index of suspicion as well as radiology, histology, immunophenotyping, and molecular analyses. We herein report a case of a 25-year-old woman presented with vaginal bleeding and a large pelvic mass involving the vaginal and uterus. A biopsy and immunohistochemical examination of the mass revealed granulocytic sarcoma, and a subsequent bone marrow biopsy confirmed the diagnosis of acute myelogenous leukemia. The patient was treated based on the standard chemotherapy followed by allogeneic bone marrow transplantation from her full-matched sibling donor. After a 9-months follow-up, there was no notable complication, and the patient is now completely disease-free. Granulocytic sarcoma of the cervix is rare, and awareness of this entity is required for timely diagnosis and effective treatment.
کلیدواژه‌ها
Granulocytic sarcomas؛ Acute myelogenous leukemia؛ Immunohistochemical؛ Myeloid sarcoma
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