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Tagajdid, Mohamed Rida, Doblali, Taoufik, Elannaz, Hicham, Hammi, Salaheddine, Belfequih, Bouchra, Mrani, Saâd. (1392). Reactivation of Cytomegalovirus in a Patient with Stevens-Johnson Syndrome-Toxic Epidermal Necrolysis. سامانه مدیریت نشریات علمی, 38(June Supplement 2013), 195-197.
Mohamed Rida Tagajdid; Taoufik Doblali; Hicham Elannaz; Salaheddine Hammi; Bouchra Belfequih; Saâd Mrani. "Reactivation of Cytomegalovirus in a Patient with Stevens-Johnson Syndrome-Toxic Epidermal Necrolysis". سامانه مدیریت نشریات علمی, 38, June Supplement 2013, 1392, 195-197.
Tagajdid, Mohamed Rida, Doblali, Taoufik, Elannaz, Hicham, Hammi, Salaheddine, Belfequih, Bouchra, Mrani, Saâd. (1392). 'Reactivation of Cytomegalovirus in a Patient with Stevens-Johnson Syndrome-Toxic Epidermal Necrolysis', سامانه مدیریت نشریات علمی, 38(June Supplement 2013), pp. 195-197.
Tagajdid, Mohamed Rida, Doblali, Taoufik, Elannaz, Hicham, Hammi, Salaheddine, Belfequih, Bouchra, Mrani, Saâd. Reactivation of Cytomegalovirus in a Patient with Stevens-Johnson Syndrome-Toxic Epidermal Necrolysis. سامانه مدیریت نشریات علمی, 1392; 38(June Supplement 2013): 195-197.

Reactivation of Cytomegalovirus in a Patient with Stevens-Johnson Syndrome-Toxic Epidermal Necrolysis

Iranian Journal of Medical Sciences
مقاله 10، دوره 38، June Supplement 2013، فروردین 2013، صفحه 195-197    اصل مقاله (181.81 K)
نوع مقاله: Case Report(s)
نویسندگان
Mohamed Rida Tagajdid* 1؛ Taoufik Doblali1؛ Hicham Elannaz1؛ Salaheddine Hammi2؛ Bouchra Belfequih1؛ Saâd Mrani1
1Laboratory of Virology, Mohamed V Souissi University, Mohamed V Military Teaching Hospital, Rabat, BP, Morocco
2Department of Internal Medicine, Mohamed V Military Teaching Hospital, Rabat, BP, Morocco
چکیده
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe adverse cutaneous reactions to drugs. We describe the case of a 19 year old patient with SJS/TEN overlap syndrome, who developed severe interstitial pneumonia after she had received antiepileptic drugs. A cytomegalovirus infection was diagnosed by Real Time Polymerase Chain Reaction (RT-PCR) detection on Bronchoalveolar lavage. Based on observations on biological data, temporal relationship, and clinical features, it could be inferred that the reactivation of cytomegalovirus with viral replication can predispose a person to TEN-SJS. We discuss here, in the light of the current literature, the probable association between drug-induced SJS-TEN and fulminant reactivation of cytomegalovirus.
کلیدواژه‌ها
Stevens-Johnson syndrome؛ Toxic epidermal necrolysis؛ Cytomegalovirus؛ Pneumonia
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