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The Mechanisms of Radiation-Induced Bystander Effect | ||
| Journal of Biomedical Physics and Engineering | ||
| مقاله 6، دوره 4، شماره 4، اسفند 2014 اصل مقاله (448.49 K) | ||
| نوع مقاله: Blackboard | ||
| نویسندگان | ||
| M Najafi* 1؛ R Fardid1؛ Gh Hadadi1؛ M Fardid2 | ||
| 1department of radiology, school of paramedical sciences, shiraz university of medical sciences, shiraz, iran | ||
| 2Health Management and Economics Research Center, Iran University of Medical Science, Tehran, Iran. | ||
| چکیده | ||
| The radiation-induced bystander effect is the phenomenon which non-irradiated cells exhibit effects along with their different levels as a result of signals received from nearby irradiated cells. Responses of non-irradiated cells may include changes in process of translation, gene expression, cell proliferation, apoptosis and cells death. These changes are confirmed by results of some In-Vivo studies. Most well-known important factors affecting radiation-induced bystander effect include free radicals, immune system factors, expression changes of some genes involved in inflammation pathway and epigenetic factors. | ||
| کلیدواژهها | ||
| Bystander effect؛ Immune system؛ Free radicals؛ Mitochondria؛ Epigenetic | ||
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