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Yavari Kia, Parisa, Baradaran, Behzad, Shahnazi, Mahnaz, Asghari Jafarabadi, Mohammad, Khaze, Vahid, Pourasad Shahrak, Shakiba. (1395). Maternal Serum and Cervicovaginal IL-6 in Patients with Symptoms of Preterm Labor. سامانه مدیریت نشریات علمی, 13(3), 229-236. doi: 10.22034/iji.2016.33411
Parisa Yavari Kia; Behzad Baradaran; Mahnaz Shahnazi; Mohammad Asghari Jafarabadi; Vahid Khaze; Shakiba Pourasad Shahrak. "Maternal Serum and Cervicovaginal IL-6 in Patients with Symptoms of Preterm Labor". سامانه مدیریت نشریات علمی, 13, 3, 1395, 229-236. doi: 10.22034/iji.2016.33411
Yavari Kia, Parisa, Baradaran, Behzad, Shahnazi, Mahnaz, Asghari Jafarabadi, Mohammad, Khaze, Vahid, Pourasad Shahrak, Shakiba. (1395). 'Maternal Serum and Cervicovaginal IL-6 in Patients with Symptoms of Preterm Labor', سامانه مدیریت نشریات علمی, 13(3), pp. 229-236. doi: 10.22034/iji.2016.33411
Yavari Kia, Parisa, Baradaran, Behzad, Shahnazi, Mahnaz, Asghari Jafarabadi, Mohammad, Khaze, Vahid, Pourasad Shahrak, Shakiba. Maternal Serum and Cervicovaginal IL-6 in Patients with Symptoms of Preterm Labor. سامانه مدیریت نشریات علمی, 1395; 13(3): 229-236. doi: 10.22034/iji.2016.33411

Maternal Serum and Cervicovaginal IL-6 in Patients with Symptoms of Preterm Labor

Iranian Journal of Immunology
مقاله 8، دوره 13، شماره 3، آذر 2016، صفحه 229-236    اصل مقاله (308.37 K)
نوع مقاله: Short Paper
شناسه دیجیتال (DOI): 10.22034/iji.2016.33411
نویسندگان
Parisa Yavari Kia1؛ Behzad Baradaran2؛ Mahnaz Shahnazi3؛ Mohammad Asghari Jafarabadi4؛ Vahid Khaze5؛ Shakiba Pourasad Shahrak* 6
1Department of Midwifery, Faculty of Nursing and Midwifery
2Immunology Research Center
3Department of Midwifery, Faculty of Nursing and Midwifer
4Prevention Research Center
5Immunology Research Center, Midwifery Student
6Department of Midwifery, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran
چکیده
Background: Preterm birth is a common problem in obstetrics.
Objective: To measure maternal serum interlukin-6 in mothers with preterm uterine contractions and compare it with cervicovaginal interlukin-6 in the same women.
Methods: In this cross-sectional study, we measured interlukin-6 in the sera and cervicovaginal fluids of 86 women with preterm uterine contractions. All participants had an intact membrane. Interlukin-6 was measured by using ELISA method. Statistical analysis was done using U-Mann Whitney, Chi-Square and Kendall’s tests. Results: The mean and median (Quartile25, Quartile75) of interlukin-6 in cervicovaginal fluid was higher than maternal serum interlukin-6. There was a statically significant difference in the median of interlukin-6 in sera and cervicovaginal fluid (P<0.0001).  There was no significant correlation between serum and cervicovaginal interlukin-6 (r=0.048, p=0.548).
Conclusion: There was no significant correlation between serum and cervicovaginal interlukin-6 (r=0.048, p=0.548). Conclusion: We found no relationship between serum interlukin-6 and preterm labor and the maternal serum Interlukin-6 does not seem to be a suitable biomarker for predicting preterm delivery.
کلیدواژه‌ها
Cervicovaginal Fluid؛ Interlukin-6؛ Maternal Serum؛ Preterm Labor
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