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Bagherian, Ali, Jafarzadeh, Abdullah, Rezaeian, Mohsen, Ahmadi, Shima, Rezaity, Mohammad Taghi. (1387). Comparison of the Salivary Immu-noglobulin Concentration Levels between Children with Early Childhood Caries and Caries-Free Children. سامانه مدیریت نشریات علمی, 5(4), 217-221. doi: 10.22034/iji.2008.17171
Ali Bagherian; Abdullah Jafarzadeh; Mohsen Rezaeian; Shima Ahmadi; Mohammad Taghi Rezaity. "Comparison of the Salivary Immu-noglobulin Concentration Levels between Children with Early Childhood Caries and Caries-Free Children". سامانه مدیریت نشریات علمی, 5, 4, 1387, 217-221. doi: 10.22034/iji.2008.17171
Bagherian, Ali, Jafarzadeh, Abdullah, Rezaeian, Mohsen, Ahmadi, Shima, Rezaity, Mohammad Taghi. (1387). 'Comparison of the Salivary Immu-noglobulin Concentration Levels between Children with Early Childhood Caries and Caries-Free Children', سامانه مدیریت نشریات علمی, 5(4), pp. 217-221. doi: 10.22034/iji.2008.17171
Bagherian, Ali, Jafarzadeh, Abdullah, Rezaeian, Mohsen, Ahmadi, Shima, Rezaity, Mohammad Taghi. Comparison of the Salivary Immu-noglobulin Concentration Levels between Children with Early Childhood Caries and Caries-Free Children. سامانه مدیریت نشریات علمی, 1387; 5(4): 217-221. doi: 10.22034/iji.2008.17171

Comparison of the Salivary Immu-noglobulin Concentration Levels between Children with Early Childhood Caries and Caries-Free Children

Iranian Journal of Immunology
مقاله 5، دوره 5، شماره 4، اسفند 2008، صفحه 217-221    اصل مقاله (89.16 K)
نوع مقاله: Original Article
شناسه دیجیتال (DOI): 10.22034/iji.2008.17171
نویسندگان
Ali Bagherian1؛ Abdullah Jafarzadeh2؛ Mohsen Rezaeian3؛ Shima Ahmadi1؛ Mohammad Taghi Rezaity2
1Department of Pediatric Dentistry, Dental School
2Department of Immunology
3Department of Epidemiology, Medical School, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
چکیده
Background: Early Childhood Caries (ECC) is one of the most common chronic child-hood diseases. In spite of the global decrease in dental caries in the past decades, ECC has become a significant problem in many developing countries and also in a few indus-trialized nations. Saliva as a host factor can play an important role in the process of den-tal caries.
Objective: The aim of this study was to compare sIgA and IgG as saliva components between ECC and caries-free groups.
Methods: In this cross-sectional study, samples of unstimulated saliva of 90 children (45 in ECC group & 45 in caries-free group) were taken with Scully method. Then the concentration levels of sIgA and IgG were measured with Enzyme Linked Immunosorbent Assay and Single Radial Im-munodiffusion methods.
Results: Mean concentration levels of salivary sIgA and IgG were significantly higher among children with ECC (p<0.05). There was also a weak inverse correlation between sIgA level and DMFT index in ECC group but it was not statistically significant (p=0.056).
Conclusion: The high concentration of salivary im-munoglobulin in children with ECC may be associated with an increased antigenic load, leading to high production of antibodies.
کلیدواژه‌ها
dental caries؛ immunoglobulins؛ Saliva
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