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Motamedifar, Mohammad, Handijani, Farhad, Hadi, Nahal, Shahkarami, Mohammad Kazem, Mehrabani, Davoud. (1384). Seroprevalence of Varicella-Zoster Virus in Children from Shiraz-Iran. سامانه مدیریت نشریات علمی, 3(1), 43-46. doi: 10.22034/iji.2006.16935
Mohammad Motamedifar; Farhad Handijani; Nahal Hadi; Mohammad Kazem Shahkarami; Davoud Mehrabani. "Seroprevalence of Varicella-Zoster Virus in Children from Shiraz-Iran". سامانه مدیریت نشریات علمی, 3, 1, 1384, 43-46. doi: 10.22034/iji.2006.16935
Motamedifar, Mohammad, Handijani, Farhad, Hadi, Nahal, Shahkarami, Mohammad Kazem, Mehrabani, Davoud. (1384). 'Seroprevalence of Varicella-Zoster Virus in Children from Shiraz-Iran', سامانه مدیریت نشریات علمی, 3(1), pp. 43-46. doi: 10.22034/iji.2006.16935
Motamedifar, Mohammad, Handijani, Farhad, Hadi, Nahal, Shahkarami, Mohammad Kazem, Mehrabani, Davoud. Seroprevalence of Varicella-Zoster Virus in Children from Shiraz-Iran. سامانه مدیریت نشریات علمی, 1384; 3(1): 43-46. doi: 10.22034/iji.2006.16935

Seroprevalence of Varicella-Zoster Virus in Children from Shiraz-Iran

Iranian Journal of Immunology
مقاله 7، دوره 3، شماره 1 - شماره پیاپی 8، خرداد 2006، صفحه 43-46    اصل مقاله (51.24 K)
نوع مقاله: Original Article
شناسه دیجیتال (DOI): 10.22034/iji.2006.16935
نویسندگان
Mohammad Motamedifar* 1؛ Farhad Handijani2؛ Nahal Hadi1؛ Mohammad Kazem Shahkarami3؛ Davoud Mehrabani4
1Departments of Bacteriology, Virology and
2Dermatology, Medical School, Shiraz University of Medical Sciences, Shiraz, Iran
3Razi Vaccine and Serum Research Institute, Tehran, Iran
4Gastroenterohepatology Research Center, Namazee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran
چکیده
Background: Varicella–zoster virus (VZV) causes herpes zoster and varicella (Chicken-pox), usually a mild disease which is diagnosed clinically with few complications. However, in neonates and healthy adults it can have a severe presentation. Herpes zoster results from VZV reactivation later in life.
Objective: To determine the seroprevalence of VZV in elementary school children aged 6-10 years in Shiraz, Iran.
Methods: A cross-sectional seroprevalence survey was conducted on 270 healthy subjects. All serum samples were investigated for immunoglobulin G (IgG) antibody against VZV using a commercial enzyme linked immunosorbent assay (ELISA).
Results: Among the studied population, 175 (64.8%) had no detectable antibody levels. The overall seroprevalence rate was 35.2%. A breakdown of seropositivity to VZV according to age was as follows; 10 years old, 50%, 9 years old, 48.2%, 8 years old, 27.3%, 7 years old, 32.1%, and 6 years old, 13.2%.
Conclusion: As VZV susceptibility in the studied age groups was higher than the expected rate, therefore childhood VZV vaccination is recommended in our region.
کلیدواژه‌ها
Seroprevalence؛ VZV؛ children؛ Iran
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